Indicated for Chronic or Small Lymphocytic Lymphoma:
Follow a weekly progress schedule over a period of 5 weeks to gradually enhance the dose to the recommended daily dose intake of 400 mg.
progress dosing schedule is generally designed to gradually decrease tumor burden and diminish risk of tumor lysis syndrome.
Week 1-20 mg orally one time a day.
Week 2-50 mg orally one time a day.
Week 3-100 mg orally one time a day.
Week 4-200 mg orally one time a day.
Week 5 and after-400 mg orally one time a day.
Monotherapy
400 mg orally every day after completing the 5-week dosage schedule.
Continue treatment until there is evidence of disease progression or the occurrence of unacceptable toxicity.
Combination with Obinutuzumab
1-cycle
Day 1- Obinutuzumab 100 mg intravenously
Day 2- Obinutuzumab 900 mg intravenously
Days 8 & 15- Obinutuzumab 1000 mg intravenously
Day 22- Start venetoclax dosing according to the 5-week ramp-up schedule.
2-cycle
Day 1- Obinutuzumab 100 mg intravenously.
Day 28-After completion of the ramp-up schedule on 2-cycle day 28, continue the venetoclax dosing 400 mg every day from 3-cycle day-1 to 12-cycle day-28.
3-6 cycle
Day 1- Obinutuzumab 100 mg intravenously.
Day 1 to 28-Continue venetoclax 400 mg orally every day.
7-12 cycle
Day 1 to 28-Continue venetoclax 400 mg orally every day.
Combination with rituximab
Venetoclax
Complete the 5-week ramp-up dosing schedule to reach 400 mg orally every day.
Continue the venetoclax dosing 400 mg orally every day for 24 months from the 1-cycle day-1 of rituximab.
Rituximab
Initiate 375 mg/m² Intravenously after the patient has received venetoclax 400 mg every day for 7 days.
500 mg/m² Intravenously on day-1 for 2-6 cycles.
Acute Myeloid Leukemia
venetoclax dosing generally depends on a combination agent.
Day 1-100 mg orally every day.
Day 2-200 mg orally every day.
Day 3-400 mg orally every day.
Day 4 and after (combination with azacitidine /decitabine): 400 mg orally every day.
Day 4 and after (combination with low dosage cytarabine): 600 mg orally every day.
combination with azacitidine, decitabine or low-dose cytarabine- Continue treatment until there is evidence of disease progression or the occurrence of unacceptable toxicity.
Canine Lymphorma (off-label)
It's recommended for treating canine lymphoma
Provide the dog with a meal just before administering this medication
Use protective disposable chemotherapy-resistant gloves while handling this drug
Initiate the administration of medication at an initial dosage of 1.25 mg per kg orally twice a week (for example, on Monday and Thursday or Tuesday and Friday), ensuring a minimum of 72 hours :
Canine Lymphorma (off-label)
It's recommended for treating canine lymphoma
Provide the dog with a meal just before administering this medication
Use protective disposable chemotherapy-resistant gloves while handling this drug
Initiate the administration of medication at an initial dosage of 1.25 mg per kg orally twice a week (for example, on Monday and Thursday or Tuesday and Friday), ensuring a minimum of 72 hours :
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Digital Certificate PDF
On course completion, you will receive a full-sized presentation quality digital certificate.
medtigo Simulation
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
medtigo Points
medtigo points is our unique point redemption system created to award users for interacting on our site. These points can be redeemed for special discounts on the medtigo marketplace as well as towards the membership cost itself.
Community Forum post/reply = 5 points
*Redemption of points can occur only through the medtigo marketplace, courses, or simulation system. Money will not be credited to your bank account. 10 points = $1.
All Your Certificates in One Place
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
