Prime Editing Unlocks a Universal Strategy for Restoring Lost Proteins
November 22, 2025
Background
Epidemiology
Anatomy
Pathophysiology
Etiology
Genetics
Prognostic Factors
Clinical History
Physical Examination
Age group
Associated comorbidity
Associated activity
Acuity of presentation
Differential Diagnoses
Laboratory Studies
Imaging Studies
Procedures
Histologic Findings
Staging
Treatment Paradigm
by Stage
by Modality
Chemotherapy
Radiation Therapy
Surgical Interventions
Hormone Therapy
Immunotherapy
Hyperthermia
Photodynamic Therapy
Stem Cell Transplant
Targeted Therapy
Palliative Care
Medication
100
mg
Orally
once a day
Loading dose (following ACS event): 180 mg orally, single dose
The maintenance dose (for 1st 12 months after diagnosis): 90 mg orally two times
The maintenance dose (after 12 months from diagnosis): 60 mg orally two times
Also, continue with aspirin 75-100 mg
25
mg
Orally 
every day
May begin as soon as 12 hours after MI
20 mg orally 2 times a day
may increase to 40 mg orally 2 times a day after 7 days
with successive titrations to the goal maintenance dosage of 160 mg twice a day as tolerated
(heart failure):
2 to 4 mg Intravenously given as a single dosage; 2 mg can be repeated at time intervals of minimum 2 hours if required. Maximum dose: 40 mg per day. Infusions can be employed at a rate of 3 mg/hr
Future Trends
References

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