Long COVID Patterns in the RECOVER-Adult Study
November 21, 2025
Background
Epidemiology
Anatomy
Pathophysiology
Etiology
Genetics
Prognostic Factors
Clinical History
Physical Examination
Age group
Associated comorbidity
Associated activity
Acuity of presentation
Differential Diagnoses
Laboratory Studies
Imaging Studies
Procedures
Histologic Findings
Staging
Treatment Paradigm
by Stage
by Modality
Chemotherapy
Radiation Therapy
Surgical Interventions
Hormone Therapy
Immunotherapy
Hyperthermia
Photodynamic Therapy
Stem Cell Transplant
Targeted Therapy
Palliative Care
Medication
ICU Patient:
Solution
Intravenous (IV)
as needed
Initial dose
0.005mg/kg/min Intravenous for 5 mins
Increase by 5-10mcg/kg/min for 5-10mins
Maintenance Dose
0.005mg/kg/min Intravenous for 5 mins
0.005mg/kg/min increase every 5 min
Prevention: 5 mg IV over 1-2 minutes at time of anesthesia induction
Treatment: 10 mg IV over 1 to 2 minutes postoperatively
ondansetron is meant for prophylaxis of nausea and vomiting caused after surgery
4 mg intravenously or intramuscularly right before the anesthesia, or
16 mg orally every hour before induction of anesthesia
Patients with body weight more than 80 kg need an additional 4 mg intravenous dose
Prophylaxis
Age 0.1-12 years
For<40 kg, 0.1 mg/kg intravenously
For >40 kg, 4 mg intravenously
Age>12 years
4 mg intravenously or intramuscularly right before anesthesia or post the procedure, or
16 mg orally an hour before anesthesia; for patients >80 kg an additional of 4 mg intravenously is preferred
As a prophylactic measure, before the reversal of anesthesia, 1 mg intravenous dose of granisetron is injected for 30 seconds
For the treatment- Undiluted 1 mg intravenously over 30 seconds
For prophylaxis
0.075 mg intravenous dose of palonosetron is infused for 10 seconds right before the anesthesia
(Off-label)
10-20 mg intramuscularly near to the end of the procedure
Repeat the dose every 4-6 hours after surgery as required
Dosing Modifications
In the case of renal impairment, when CrCl is less than 40ml/min, decrease the dose by half
And when CrCl is less than 10ml/min, decrease the dose by three-fourth
(Off-label)
0.1-2 mg/kg intravenously every 6-8 hours as required
In 2 mL of the isotonic saline solution, administer 0.2 ml
Apply one patch transdermal behind the ear prior to surgery in the evening or an hour before the C-section
(Off-label)
0.1-2 mg/kg intravenously every 6-8 hours as required
Not recommended for use in children below ten years of age
For children of age more than ten years of age:
Apply one patch transdermal behind the ear prior to surgery in the evening or an hour before the C-section
As a prophylactic measure, before the reversal of anesthesia, 1 mg intravenous dose of granisetron is injected for 30 seconds
For the treatment- Undiluted 1 mg intravenously over 30 seconds
Future Trends
References

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