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Brand Name :
Audmonal, Spasmonal
Synonyms :
Alverine citrate
Class :
Antispasmodic agents
Dosage Forms & Strengths
Capsules
60mg
120mg
60 - 120
mg
Capsules
Orally
3 times a day
Dosage Forms & Strengths
Capsules
60mg
120mg
60 - 120
mg
Capsules
Orally
3 times a day
Note: this is not recommended for children under the age of 12 years
Indications: this is indicated for use in painful cramps during periods, irritable bowel syndrome, diverticular disease, etc.
Refer to adult dosing.
the risk of adverse effects may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
amitriptylinoxide(Phase 4 Clinical Trials)
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
an increase in CNS depressant activity of alverine may be increased
the risk of CNS depression may be increased
the risk of CNS depression may be increased
Actions and spectrum:
Alverine citrate works to relax smooth muscles. It relieves pain from intestines and uterus. The medicine targets these muscles. These muscles get relaxed. The medicine functions as a smooth muscle relaxant.
Frequency not defined
Dizziness
Shortness of breath
Headache
Nausea
Itching
Rashes on skin
Hepatitis
Swollen lips, tongue
Overdose effects
Increased heart rate
Blurred vision
Black Box Warning
No specific warnings are available for this drug
Contraindication/Caution:
Contraindication:
Hypersensitivity
Paralytic ileus
Intestinal obstruction
Caution:
Abnormal vaginal bleeding
Severe constipation
Loss of appetite
Blood from bowel
Weight loss
Pregnancy
Contraindication/Caution:
Contraindication:
Hypersensitivity
Paralytic ileus
Intestinal obstruction
Caution:
Abnormal vaginal bleeding
Severe constipation
Loss of appetite
Blood from bowel
Weight loss
Pregnancy
Pharmacology:
Alverine works by relaxing smooth muscles. It exerts its effect as an antispasmodic agent. Muscles become less tense and spasms decrease, providing relief.
Pharmacodynamics:
Alverine is a drug that relaxes involuntary muscles. It acts on the smooth muscles in the uterus and stomach. By directly impacting the intestinal muscles, Alverine prevents spasms. These spasms are linked to conditions like diverticular disease and irritable bowel syndrome.
Pharmacokinetics:
Metabolism
Alverine quickly transforms into its potent form. This compound then shifts into two secondary byproducts. After conversion, the substance undergoes additional changes, giving rise to two distinct metabolites.
Elimination and excretion
Alverine gets removed quickly from the body through the kidneys. Its removal time is brief, around 0.8 hours. However, one of its broken down products lasts longer, around 5.7 hours, before being removed.
Administration:
Alverine capsules should be taken orally with plenty of water with or without meals
Do not chew the capsules
Patient information leaflet
Generic Name: alverine citrate
Why do we use alverine citrate?
Alverine citrate treats muscle spasms. This drug helps with irritable bowel syndrome (IBS). It also helps with primary dysmenorrhea and diverticular colon disease. Alverine citrate stops IBS symptoms like constipation and diarrhea. It stops the urge to urinate and bloating too. The medication soothes spasming smooth muscles to provide relief.