Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Bepreve
Synonyms :
bepotastine
Class :
Antihistamines, Ophthalmic
Dosage forms & Strengths:
Adult:
Ophthalmic solution
1.5% (10 ml)
Ophthalmic solution
1.5% (10 ml)
Refer to the adult dosing
bepotastine: it may increase the risk of methemoglobinemia agents
bepotastine: it may increase the risk of methemoglobinemia agents
bepotastine: it may increase the risk of methemoglobinemia agents
bepotastine: it may increase the risk of methemoglobinemia agents
bepotastine: it may increase the risk of methemoglobinemia agents
bepotastine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
tinidazole has the potential to reduce the rate of excretion of bepotastine, potentially leading to an elevation in level of serum
bepotastine leads to a reduction in the rate of excretion of eucalyptus oil which leads to increased level of serum
cefpirome leads to a reduction in the rate of excretion of bepotastine which leads to increased level of serum
bepotastine leads to a reduction in the rate of excretion of chromous sulfate, which leads to an increased level of serum
bepotastine leads to a reduction in the rate of excretion of pentaerythritol tetranitrate, which leads to an increased level of serum
bepotastine leads to a reduction in the rate of excretion of potassium acetate, which leads to an increased level of serum
bepotastine leads to a reduction in the rate of excretion of potassium perchlorate, which leads to an increased level of serum
bepotastine may decrease the excretion rate of almasilate, leading to higher serum levels
the rate of excretion of inositol may be reduced
the rate of excretion of bepotastine may be reduced
bepotastine might lead to a reduction in the rate of excretion of telavancin, potentially leading to elevated levels of serum
ceforanide: it may decrease the excretion rate of bepotastine
Actions and Spectrum:
Actions:
bepotastine works by blocking the effects of histamine, a chemical released in response to an allergen and causes the symptoms of an allergy.
Spectrum:
bepotastine is primarily used to treat symptoms of allergic rhinitis (hay fever) and allergic conjunctivitis (eye allergies). It has also been used to treat itching associated with skin conditions such as atopic dermatitis and urticaria.
Frequency Defined
10%:
Mild disturbance in taste
1-10%:
Ocular irritation (2-5%)
Nasopharyngitis (2-5%)
Headache (2-5%)
Contraindication/Caution:
Cautions:
Pregnancy consideration:
The drug is not recognized during pregnancy.
Breastfeeding warnings:
No data is available regarding the excretion of the drug in breast milk.
Pregnancy category:
Category A: well-controlled and satisfactory studies do not show risk to the fetus in the first/later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology:
bepotastine is an antihistamine medication that works by blocking the effects of histamine, a chemical released in response to an allergen and causes the symptoms of an allergy.
The mechanism of action of bepotastine involves binding to histamine H1 receptors in the body and blocking the effects of histamine. By blocking the effects of histamine, bepotastine reduces the symptoms of allergies, such as itching, runny nose, sneezing, and watery eyes.
Pharmacodynamics:
bepotastine is a selective histamine H1 receptor antagonist which specifically targets and blocks the histamine H1 receptors in the body. By blocking the histamine H1 receptors, bepotastine reduces the symptoms of allergies, such as itching, runny nose, sneezing, and watery eyes
Pharmacokinetics:
The pharmacokinetics of bepotastine are as follows
Absorption
The drug is absorbed systemically
The value of Cmax is 5.1-7.3 ng/mL
Distribution
Protein-bound is 55%
Peak serum time is 1-2 hours
Metabolism
The drug is metabolized minimally by CYP450 isozymes
Elimination
The drug is excreted 75-90% in urine
Administration:
bepotastine is an antihistamine medication that treats allergy symptoms such as itching, redness, and watery eyes. It is usually administered orally in the form of tablets or capsules.
The recommended dose for adults is usually one tablet (1.5 mg or 5 mg) taken once a day. However, the specific dose and frequency of administration may vary depending on the patient’s condition and response to treatment.
Patient information leaflet
Generic Name: bepotastine
Pronounced: BEP-oh-TAS-teen
Why do we use bepotastine?
bepotastine treats many allergy symptoms, including seasonal allergies, hay fever, and allergic conjunctivitis. It is also used to treat symptoms of skin allergies, such as itching and redness, and can effectively relieve hives’ symptoms.
In addition to its antihistamine effects, bepotastine has anti-inflammatory properties. They help to reduce swelling and redness associated with allergies.
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