Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Synonyms :
cholestyramine
Class :
Bile Acid Sequestrants
Brand Name :
Synonyms :
cholestyramine
Class :
Bile Acid Sequestrants
Dosage Forms & StrengthsÂ
Adult Â
PacketÂ
4 gÂ
Powder for oral suspensionÂ
231 gÂ
378 gÂ
210 gÂ
4 g orally every 1-2 times a day; progressively increase over more than 1-month intervals
Maintenance: 8-16 g daily Orally divided every 12 hours; should not exceed more than 24 g/day.
Overdose: Gastrointestinal obstruction is one of the symptoms; therapy is supportive.
Dosage Forms & StrengthsÂ
Powder for oral suspensionÂ
5 gÂ
5.5 g Â
5.7 g Â
6.4 g Â
9 g Â
240 mg/kg daily orally divided every 8-12hours; generally, should not exceed more than 8g/day
Refer to the adult dosing regimenÂ
they may diminish the serum concentration when combined with fluvastatin
they may diminish the serum concentration when combined with rosiglitazone
they may diminish the serum concentration when combined with valproic acid
they may diminish the serum concentration when combined with vitamin k antagonists
they may diminish the serum concentration when combined with vitamin k antagonists
they may diminish the serum concentration when combined with vitamin k antagonists
they may diminish the serum concentration when combined with vitamin k antagonists
they may diminish the serum concentration when combined with vitamin k antagonists
they may diminish the serum concentration when combined with mycophenolate
they may have an increasingly adverse effect when combined with spironolactone
It may diminish the effect when combined with cholic acid by drug binding in the gastrointestinal tract
It may diminish the effects when combined with vitamin D
Action and Spectrum:Â
Cholestyramine resin is a bile acid sequestrant that limits reabsorption in the gastrointestinal tract. It is a strong anion exchange resin that forms a matrix with anionic bile acids.Â
Frequency not definedÂ
BelchingÂ
FlatulenceÂ
GallstonesÂ
HeartburnÂ
Malabsorption of fat-soluble vitaminsÂ
Nausea and vomitingÂ
PancreatitisÂ
Dental erosionÂ
Duodenal ulcer bleedingÂ
Perianal irritationÂ
Rectal painÂ
SteatorrheaÂ
Black box warning:Â
None Â
Contraindications/caution:Â
Contraindications:Â
Hypersensitivity to bile-sequestering resinsÂ
Complete biliary obstructionÂ
Cautions:Â
Renal impairmentÂ
Volume depletionÂ
Concomitant spironolactone therapyÂ
Pregnancy Warnings:Â
Pregnancy category: CÂ
Lactation: Excretion of the drug into the human breast milk is unknownÂ
Pregnancy categories:Â
Pharmacology: Cholestyramine binds to bile acids in the intestine to prevent reabsorption into circulation. Then liver convert more cholesterol to bile acids for cover the losses.Â
Pharmacodynamics: Cholestyramine resin binds with bile acids in the intestine to form an insoluble complex excreted in feces. All bile acids are absorbed in the intestinal tract and recycled into the liver. Â
Pharmacokinetic:Â
Absorption:Â
It is not absorbed from the gastrointestinal tract.Â
Excretion and elimination:Â
It is excreted through feces.Â
Administration:Â
It is available in packet and powder (suspension) form for oral use.Â
Patient information leaflet:Â
Generic Name: CholestyramineÂ
Why do we use Cholestyramine?Â
Cholestyramine is indicated in the treatment of hyperlipidemia.Â
It is also used to treat hypercholesterolemia and bile acid diarrhea.Â
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