cinchocaine hydrochloride/fluocortolone hexanoate/fluocortolone pivalate

Action and Spectrum

Actions and spectrum:  

In this combination medication, the cinchocaine hydrochloride has a local anaesthetic effect. 

While fluocortolone is belongs to a group of the corticosteroids which reduce inflammation and itching.  

Drug Interaction

Adverse Reaction

Adverse reaction  

None  

Black Box Warning

Black Box Warning    

None  

Contraindication / Caution

Contraindication/Caution:  

None  

Pregnancy / Lactation

Pregnancy Warnings: 

Pregnancy category: N/A 

Lactation: Excretion of the drug into the human breast milk is unknown 

Pregnancy categories: 

Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester. 

Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women. 

Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women. 

Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits. 

Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women. 

Category N: There is no data available for the drug under this category. 

Pharmacology

Pharmacology  

Cinchocaine hydrochloride has a local anaesthetic effect on mucous membranes. 

Fluocortolone hexanoate is a topically active corticosteroid and has anti-inflammatory properties. 

Fluocortolone pivalate is a rapid-acting ester of fluocortolone. 

Pharmacodynamics:  

Limited information is available. 

Pharmacokinetics:  

Limited information is available on ADME.  

Adminstartion

Administration:  

It is applied topically around anus in the form of ointment. 

Patient Information Leaflet

Patient information leaflet  

Generic Name: cinchocaine hydrochloride/fluocortolone hexanoate/fluocortolone pivalate 

Why do we use cinchocaine hydrochloride/fluocortolone hexanoate/fluocortolone pivalate? 

It is combination drug used to provide relief from inflammation, swelling, itching and soreness of piles and to relieve itching of the anus.