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Brand Name :
N/A
Synonyms :
Coleus barbatus, Forskolina, Coleus forskohlii, Plectranthus barbatus
Class :
Pulmonary, Oncology, Cardiovascular, Neurology & Psychiatry, Gastrointestinal, Herbals
Brand Name :
N/A
Synonyms :
Coleus barbatus, Forskolina, Coleus forskohlii, Plectranthus barbatus
Class :
Pulmonary, Oncology, Cardiovascular, Neurology & Psychiatry, Gastrointestinal, Herbals
Dosage forms and strengths
100 mg
300 mg
(10 to 20 % forskolin)
Extract: Inhalation
Powder 10 mg
Pediatric
Safety and efficacy are not seen in pediatrics
Geriatric
Refer to the adult dosing
both forskolin and aceclofenac enhance anticoagulation
both forskolin and acemetacin enhance anticoagulation
both forskolin and diclofenac enhance anticoagulation
both forskolin and agrimony enhance anticoagulation
both forskolin and alfalfa enhance anticoagulation
both forskolin and alteplase enhance anticoagulation
both forskolin and aspirin enhance anticoagulation
both forskolin and enoxaparin enhance anticoagulation
both forskolin and heparin enhance anticoagulation
Actions and Spectrum:
Action:
Forskolin, extracted from coleus forskohlii roots, activates adenylate cyclase enzyme, increasing cAMP levels in cells, leading to various physiological effects.
Forskolin may dilate blood vessels, lowering blood pressure, and has positive effects on heart contractions.
Spectrum:
Coleus has been used in Ayurveda for digestive, skin, and respiratory issues.
Modern research focuses on coleus forskohlii for heart health, weight management, and inflammation.
Frequency not defined
Diarrhea
GI syndrome
CNS depression
Perianal dermatitis
Arrhythmias
Tachycardia
Black Box Warning:
Take caution in bleeding disorders.
Contraindication/Caution:
Contraindications
Cautions
Pregnancy/Lactation
Pregnancy consideration:
No data is available regarding the administration of the drug during pregnancy.
Breastfeeding warnings:
No data is available regarding the excretion of drug in breast milk.
Pregnancy category:
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: There was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: There was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: Adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology
Forskolin, derived from coleus root, is its main active compound, extensively studied for its pharmacological effects.
Pharmacodynamics
Forskolin activates adenylyl cyclase, boosting cAMP production, causing smooth muscle relaxation with therapeutic implications for conditions like asthma.
Pharmacokinetics:
Limited data available
Administration:
Coleus supplements with forskolin extract come in capsules, tablets, or liquid forms for oral intake.
Patient information leaflet
Generic Name: coleus
Pronounced: KOH-lee-us
Why do we use coleus?
Ayurveda uses herbs for respiratory, heart, and digestive problems. Forskolin from coleus forskohlii may help with weight, heart, and breathing. Be cautious and consult a healthcare professional for its use due to ongoing research on effectiveness and safety.
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