Actions and spectrum:
dactinomycin is an antineoplastic agent that works by inhibiting DNA and RNA synthesis. It is a cytotoxic antibiotic produced by the bacterium Streptomyces parvulus.
It is a broad spectrum of activity against various tumor types and is used in the treatment of various types of cancer, including Wilms’ tumor, rhabdomyosarcoma, Ewing’s sarcoma, testicular cancer, gestational trophoblastic neoplasia, and childhood tumors.
It is used as a component of multi-agent chemotherapy regimens for the treatment of osteosarcoma and other malignancies. dactinomycin can be used alone or in combination with other anticancer drugs
