Microplastics and Misinformation: What Science Really Says
November 12, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Parvodex
Synonyms :
dextropropoxyphene
Class :
Opioid analgesic
Brand Name :
Parvodex
Synonyms :
dextropropoxyphene
Class :
Opioid analgesic
Not determined
Refer to adult dosing
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
it may diminish the metabolism when combined with ciclesonide
When encainide is used together with dextropropoxyphene, this leads to a reduction in the encainide’s metabolism
When dextropropoxyphene is used together with melitracen, this leads to enhanced risk or seriousness of CNS depression
When indisulam is used together with dextropropoxyphene, this leads to a reduction in dextropropoxyphene metabolism
When dextropropoxyphene is used together with profenamine, this leads to enhanced risk or seriousness of adverse events
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
asenapine: it may increase the risk of CNS depression with dextropropoxyphene
astemizole: it may increase the serum concentration of dextropropoxyphene
asunaprevir: it may decrease the metabolism of dextropropoxyphene
atazanavir: it may decrease the metabolism of dextropropoxyphene
atenolol: it may decrease the metabolism of dextropropoxyphene
bimekizumab: it may increase the metabolism of dextropropoxyphene
bisoxatin: it may decrease the therapeutic efficacy of dextropropoxyphene
boceprevir: it may decrease the therapeutic efficacy of dextropropoxyphene
cephalexin: it may decrease the therapeutic efficacy of dextropropoxyphene
ceritinib: it may decrease the therapeutic efficacy of dextropropoxyphene
cerivastatin: it may decrease the therapeutic efficacy of dextropropoxyphene
cetirizine: it may decrease the therapeutic efficacy of dextropropoxyphene
Actions and Spectrum
dextropropoxyphene is an opioid analgesic, which means it acts on opioid receptors in the brain and spinal cord to relieve pain. It has both analgesic and antitussive properties.
Frequency not defined
Tremors
Vomiting
Abdominal pain
Dizziness
Rash
Itching of skin
Nausea
Headache
Diarrhea
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Alcohol consumption should be avoided while taking dextropropoxyphene, as it can increase the risk of side effects and respiratory depression.
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:     
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
dextropropoxyphene works by binding opioid receptors in the brain and spinal cord.
Activation of these receptors leads to various effects, including pain relief, and a sense of euphoria or relaxation.
Pharmacodynamics
dextropropoxyphene binding to mu opioid receptors results in pain relief. It changes the feeling of pain and reduces the transmission of pain signals in the brain and spinal cord.
Pharmacokinetics
Absorption
dextropropoxyphene is well absorbed from the gastrointestinal tract.
Distribution
dextropropoxyphene is distributed widely throughout the body.
Metabolism
dextropropoxyphene is primarily metabolized in the liver.
Elimination and excretion
dextropropoxyphene is excreted through renal route.
Administration
dextropropoxyphene is taken orally and it is available in the form of tablets and capsules.
Patient information leaflet
Generic Name: dextropropoxyphene
Why do we use dextropropoxyphene?
Parvodex (dextropropoxyphene) is generally used for the relief of moderate to severe pain.
dextropropoxyphene acts as an opioid analgesic and binds with opioid receptors to reduce the intensity of pain.
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
