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Brand Name :
Arixtra
Synonyms :
fondaparinux
Class :
Anti-coagulants, Hematologic, factor Xa inhibitors
Brand Name :
Arixtra
Synonyms :
fondaparinux
Class :
Anti-coagulants, Hematologic, factor Xa inhibitors
Dosage Forms & StrengthsÂ
Prefilled syringe:Â
2.5mg/0.5mlÂ
5mg/0.4mlÂ
7.5mg/0.6mlÂ
10mg/0.8mlÂ
Prevention:
>50kg:2.5mg sub-cutaneously daily once for 5-9 days
Treatment
<50kg:5mg subcutaneous daily once
50-100kg:7.5mg subcutaneous daily once
>100kg:10mg subcutaneous daily once
Treatment for 5-9 days
2.5
mg
Solution
Subcutaneous (SC)
daily once
5 - 10
days
Refer adult dosingÂ
may increase the anti coagulant activity
may enhance the effects of the other by pharmacodynamic synergism
may enhance the effects of the other by pharmacodynamic synergism
may increase the metabolism of each other
may enhances the effects of the other by pharmacodynamic synergism
may enhances the effects of the other by pharmacodynamic synergism
may increase the levels of each other by decreasing the metabolism
may increase the levels of each other by decreasing the metabolism
may increase the levels of each other by decreasing the metabolism
when both drugs are combined, there may be an increased effect of fondaparinux by anticoagulation  
when both drugs are combined, there may be an increased effect of fondaparinux by anticoagulation  
relugolix/​estradiol/​norethindroneÂ
may diminish the effects of each other by pharmacodynamic antagonism
the risk of bleeding may be increased
It may enhance the risk of bleeding by affecting coagulation when combined with omega-3 carboxylic acids
when both drugs are combined, the risk or severity of bleeding increases  
reduce therapeutic effects of fondaparinux
gemcitabine, by the unspecific reactions, increases the effect of fondaparinux
the effect of fondaparinux is increased by fluorouracil with the help of an unspecific interaction mechanism
demeclocycline increases the effects of fondaparinux by an unknown mechanism
doxycycline increases the effects of fondaparinux by an unknown mechanism
Frequency defined:Â Â
>10%Â
NauseaÂ
FeverÂ
AnemiaÂ
1-10%Â
DizzinessÂ
RashÂ
HeadacheÂ
InsomniaÂ
EdemaÂ
Urinary retentionÂ
VomitingÂ
hypotensionÂ
Pregnancy consideration: CÂ
Lactation: The drug is excreted in the breast milkÂ
Pregnancy category:Â
Patient information leafletÂ
Generic Name: FondaparinuxÂ
Pronounced: fon-da-par-i-nuxÂ
Why do we use fondaparinux?Â
Fondaparinux is a medication used to treat deep vein thrombosis, a condition in which dangerous blood clots develop in the blood arteries of the legsÂ
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