magnesium silicate

Action and Spectrum

Actions and Spectrum 

The missing component is substituted by magnesium silicate. The primary function of antacids, when it comes to the absorption of hydrochloric acid, is that they are non-absorbable.

Drug Interaction

Adverse Reaction

Frequency not defined  

Sweating 

Hypotension  

Depressed reflexes  

Hypothermia 

Circulatory collapse 

Black Box Warning

Black Box Warning 

None 

Contraindication / Caution

Contraindication/Caution: 

None 

Pregnancy / Lactation

Pregnancy consideration: 

Pregnancy category: N/A 

Lactation: Excretion into human milk is unknown  

Pregnancy Categories:         

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester. 

Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.  

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women. 

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits. 

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women. 

Category N: There is no data available for the drug under this category. 

Pharmacology

Pharmacology  

Magnesium silicate has astringent and neutralizing properties.  

Magnesium oxide and silicon combine to form magnesium silicate. It is silicic acid magnesium salt with an arbitrary amount of water. 

Pharmacodynamics 

When talc is injected into the pleural cavity, it induces an inflammatory response, which has a therapeutic effect. This response encourages the visceral and parietal pleura to adhere to one another, obliterating the pleural space and preventing pleural fluid from reaccumulating. 

Pharmacokinetics 

Limited information available on ADME. 

Adminstartion

Administration 

Magnesium silicate is available in topical formulations, such as tablet, liquid, and powders. 

Patient Information Leaflet

Patient information leaflet 

Generic Name: magnesium silicate 

Why do we use magnesium silicate? 

Magnesium silicate also referred to as talc and it is useful substance for keeping skin dry and preventing rashes because it reduces friction and absorbs moisture well.  

For those who are deficient in magnesium silicate, dietary supplements containing magnesium silicate are used. Magnesium silicate is also used in treatment of hypomagnesemia.