One Cup of Coffee a Day Keeps AF Away? Insights from the DECAF Trial
November 10, 2025
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Brand Name :
Elahere, mirvetuximab soravtansine-gynx
Synonyms :
mirvetuximab soravtansine, mirvetuximab soravtansine-gynx
Class :
Anti-neoplastic, monoclonal antibody
Brand Name :
Elahere, mirvetuximab soravtansine-gynx
Synonyms :
mirvetuximab soravtansine, mirvetuximab soravtansine-gynx
Class :
Anti-neoplastic, monoclonal antibody
Dosage Forms & Strengths
Injectable solution
100mg/20ml(5mg/ml)
6
mg/kg
Solution
Intravenous (IV)
every 3 weeks
continue until disease progress
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may decrease the therapeutic effect of Fc receptor binding agents
Frequency defined:
>10%
All grades
AST increased
Nausea
Keratopathy
Decreased lymphocytes
Diarrhea
Increased alkaline phosphatase
Decreased leukocytes
Decreased hemoglobin
Cataract
Decreased platelets
Arthralgia
Dyspnea
Increased creatinine
Dry eye
Constipation
Peripheral neuropathy
Decreased albumin
1-10%
All grades
Myalgia
Pneumonitis
Uveitis
Eye pain
Hypersensitivity
Thrombocytopenia
Grades 3-4
Increased alkaline phosphatase
Decreased albumin
Decreased magnesium
Dry eye
Fatigue
Vision impairment
Decreased neutrophils
Keratopathy
Increased AST/ALT
Decreased appetite
Decreased hemoglobin
Cataract
Keratopathy
Abdominal pain
Pregnancy consideration: Insufficient data available
Lactation: Excretion of the drug in human breast milk is unknown
Pregnancy category:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient information leaflet
Generic Name: mirvetuximab soravtansine
Pronounced: mir” ve tux’ i mab soe” rav tan’ seen
Why do we use mirvetuximab soravtansine?
It is used to treat fallopian tube or ovarian cancer.
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