What Happens When You’re Just Mind Blanking
December 27, 2025
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Brand Name :
Vigamox, Moxeza
Synonyms :
moxifloxacin ophthalmic
Class :
Quinolones, Ophthalmic
Brand Name :
Vigamox, Moxeza
Synonyms :
moxifloxacin ophthalmic
Class :
Quinolones, Ophthalmic
Dosage Forms & Strengths
Ophthalmic solution
0.5%
Put 1 drop into the affected eyes every 12 hours for seven days
Dosage Forms & Strengths
Ophthalmic solution
0.5%
<4 months: Safety and efficacy not determined
>4 months:
Put 1 drop into the affected eye every 12 hours
Refer to adult dosing
Actions and Spectrum
moxifloxacin ophthalmic works by inhibiting the activity of bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for bacterial DNA replication, transcription, repair, and recombination.
moxifloxacin ophthalmic has a broad-spectrum of activity against various gram-positive and gram-negative bacteria, including some drug-resistant strains.
Frequency defined
1-10%
Rash
Subconjunctival hemorrhage
Tearing
Ocular discomfort
Fever
Rhinitis
Otitis media
Infection
Ocular pruritus
Pharyngitis
Ocular pain
Increased cough
Ocular hyperemia
Conjunctivitis
Dry eye
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
moxifloxacin ophthalmic disrupts the bacterial cell’s ability to replicate and divide results in leading to cell death or inhibition of bacterial growth.
Pharmacodynamics
moxifloxacin ophthalmic exhibits concentration-dependent bactericidal activity, meaning its killing effect on bacteria is directly related to the drug concentration at the site of action.
Pharmacokinetics
Absorption
moxifloxacin ophthalmic is absorbed through the cornea and conjunctiva.
Distribution
moxifloxacin ophthalmic may distribute within the anterior chamber of the eye and surrounding tissues.
Metabolism
moxifloxacin ophthalmic undergoes hepatic metabolism.
Elimination and excretion
moxifloxacin ophthalmic drug is not excreted in the urine.
Administration
moxifloxacin ophthalmic drug is available as eye drops or ointments for topical use.
Patient information leaflet
Generic Name: moxifloxacin ophthalmic
Why do we use moxifloxacin ophthalmic?
moxifloxacin ophthalmic is used to treat bacterial conjunctivitis.
moxifloxacin ophthalmic is also effective in treating corneal ulcers caused by bacterial infections.
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