Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Opilon
Synonyms :
moxisylyte
Class :
Peripheral Vasodilators, Cerebral Activators
Brand Name :
Opilon
Synonyms :
moxisylyte
Class :
Peripheral Vasodilators, Cerebral Activators
Dosage Forms & Strengths
Tablet
40 mg
Take a dose of 40 mg orally four times in a day and it may be raised up to 80 mg four times daily if required
Not determined
Refer to adult dosing
moxisylyte: it may increase the hypotensive activities of alfuzosin
moxisylyte: it may decrease the antihypertensive activities of aliskiren
moxisylyte: it may decrease the excretion rate of benserazide
moxisylyte: it may decrease the excretion rate of benznidazole
moxisylyte: it may decrease the excretion rate of carbamazepine
alclofenac: it may increase the risk of hypertension with moxisylyte
aldesleukin: it may decrease the excretion rate of moxisylyte
allopurinol: it may decrease the excretion rate of moxisylyte
benzonatate: it may increase the serum concentration of moxisylyte
benzphetamine: it may decrease the therapeutic efficacy of moxisylyte
benzthiazide: it may increase the excretion rate of moxisylyte
carbidopa: it may decrease the excretion rate of moxisylyte
carboplatin: it may decrease the excretion rate of moxisylyte
cariprazine: it may increase the risk of hypertension with moxisylyte
carprofen: it may increase the risk of hypertension with moxisylyte
Actions and Spectrum
moxisylyte works by relaxing the smooth muscles in the walls of blood vessels, particularly in arteries. This relaxation leads to the dilation of blood vessels. It reduces the response of blood vessels to norepinephrine, a neurotransmitter that constricts blood vessels.
Frequency not defined
Vertigo
Diarrhea
Nausea
Headache
Rash
Facial flushing
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
moxisylyte is classified as an alpha-1 adrenergic receptor antagonist. It works by blocking alpha-1 adrenergic receptors in smooth muscle cells within blood vessel walls.
Alpha-1 adrenergic receptors are typically activated by norepinephrine, leading to smooth muscle contraction and vasoconstriction.
Pharmacodynamics
Vasodilation caused by moxisylyte results in a decrease in systemic vascular resistance. This decrease in resistance leads to a reduction in blood pressure.
moxisylyte can cause a significant drop in blood pressure, potentially resulting in hypotension.
Pharmacokinetics
Absorption
moxisylyte is rapidly absorbed after oral administration.
Distribution
moxisylyte is distributed throughout the body.
Metabolism
moxisylyte undergoes metabolism in the liver.
Elimination and excretion
moxisylyte is primarily excreted through the urine.
Administration
moxisylyte is available in tablet or capsule form for oral administration.
Patient information leaflet
Generic Name: moxisylyte
Why do we use moxisylyte?
moxisylyte is used to treat Raynaud’s disease, a condition characterized by the constriction of blood vessels.
moxisylyte is used to treat erectile dysfunction by increasing blood flow to the penis.
moxisylyte is also indicated for the symptomatic management of sequelae of cerebral infarction or hemorrhage.
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