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November 22, 2025
Brand Name :
Pivicil, Relexid, Selexid, Xsysto, Alexid, Vacilex, Emcil, Lexipen, Melysin, Panomax, Pivmecillinam
Synonyms :
pivmecillinam
Class :
Antibiotics & penicillin (beta-lactams)
Dosage forms & StrengthsÂ
Tablet (film coated), Oral:Â
200 mgÂ
20 - 40
mg/kg
Tablet
daily in 3 to 4 divided doses
Chronic Or Recurrent Bacteriuria
200
mg
Orally 
twice a day
7
days
Or
200 mg orally thrice a day for 5 days
200
mg
Orally 
twice a day
day for 7 days
Or
200 mg orally thrice a day for 5 days
Dosage forms & StrengthsÂ
Tablet (film coated), Oral:Â
200 mgÂ
Chronic Or Recurrent Bacteriuria
For children > 40kg only: :
400
mg
3 to 4 times a day
Chronic Or Recurrent Bacteriuria
For children > 40kg only: :
400
mg
3 to 4 times a day
Chronic Or Recurrent Bacteriuria
For children > 40kg only: :
400
mg
3 to 4 times a day
For children > 40kg only::
20 - 40
mg/kg
Tablet
Orally 
daily in 3 to 4 divided doses
Refer to adult dosingÂ
tetracycline may decrease the therapeutic effects of penicillins by interfering with its bactericidal effects
tetracycline may decrease the therapeutic effects of penicillins by interfering with its bactericidal effects
Interaction with pivmecillinam may enhance the serum concentration of methotrexate
Interaction with pivmecillinam may enhance the serum concentration of methotrexate
Concomitant use of pivmecillinam and willow bark may result in increased levels of both drugs due to decreased renal clearance
acemetacin may increase the serum concentration of penicillins
penicillins may iincrease the anticoagulant effect of Vitamin K Antagonists
penicillins may decrease serum concentrations of the active metabolite(s) of mycophenolate
bismuth subcitrate, metronidazole and tetracycline
may decrease the therapeutic effect when combined with penicillins
may decrease the therapeutic effect when combined with penicillins
may decrease the therapeutic effect when combined with penicillins
may decrease the therapeutic effect when combined with penicillins
may decrease the therapeutic effect when combined with penicillins
Frequency defined:Â Â
>10% (significant):Â
Carnitine deficiency Â
>10% (Prolong use):Â
Acute porphyria Â
1% to 10% (Prolong use):Â
ThrombocytopeniaÂ
VertigoÂ
NauseaÂ
DiarrheaÂ
VomitingÂ
Abdominal painÂ
Oesophageal ulcerÂ
Mouth ulcerationÂ
FatigueÂ
RashÂ
DizzinessÂ
HeadacheÂ
Pregnancy considerations: pivmecillinam can be assigned under pregnancy category D. Avoid during pregnancy.Â
Lactation: Pivmecillinam can be excreted in breast milk and may cause tooth discoloration in infants. Avoid use during breastfeeding. Â
Pregnancy category:Â
Â
Patient information leafletÂ
Generic Name: PivmecillinamÂ
Pronunciation: Piv-mecill-inam Â
Why do we use pivmecillinam?Â
Pivmecillinam is a beta-lactam derivative antibiotic drug. It is used to treat bacterial infections.