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Brand Name :
pravachol
Synonyms :
Pravastatin acid, pravastatina
Class :
Lipid-lowering agents, HMG-CoA reductase inhibitors, statin
Dosage Forms & Strengths
Tablet
10mg
20mg
40mg
80mg
10 - 40
mg
Tablets
Orally
every day
Do not exceed 80mg/day
Dosage Forms & Strengths
Tablet
10mg
20mg
40mg
80mg
Heterozygous Familial Hypercholesterolemia
8-13 years:
20
mg
Tablet
Orally
every day
14-18 years: 40mg orally every day
Administered with cyclosporin-Initiate with 10mg every night at bedtime
Do not exceed 20mg/day
may enhance the myopathic (rhabdomyolysis) effect
may enhance the serum concentration
may enhance the serum concentration
may intensify the effect of HMG-CoA Reductase Inhibitors on myopathic (rhabdomyolysis) disease
may diminish the serum concentration
may intensify the potentially negative effects of HMG-CoA Reductase Inhibitors
may enhance the serum concentration
may intensify the potentially negative effects of HMG-CoA Reductase Inhibitors
may intensify the effect of HMG-CoA Reductase Inhibitors on myopathic (rhabdomyolysis) disease
may enhance HMG-CoA Reductase Inhibitors' serum levels
may diminish the serum concentration
may intensify the potentially negative effects of HMG-CoA Reductase Inhibitors
may enhance HMG-CoA Reductase Inhibitors' serum levels
may enhance the serum concentration
may enhance the serum concentration
may enhance the serum concentration
may enhance the serum concentration
may enhance the serum concentration
may intensify the effects of HMG-CoA Reductase Inhibitors
may diminish the serum concentration
may intensify the potentially negative effects of HMG-CoA Reductase Inhibitors
may enhance the serum concentration
may enhance the serum concentration
When pravastatin is used together with ouabain, this leads to reduction in pravastatin excretion
It may enhance the risk of adverse effects when combined with antihyperlipidemic
It may enhance the risk of adverse effects when combined with antihyperlipidemic
It may enhance the risk of adverse effects when combined with antihyperlipidemic
may have a decrease in excretion when combined with pravastatin
Frequency defined:
1-10%
Chest pain
Heartburn
Diarrhea
Cough
Myalgia
Headache
Flu-like symptoms
Rash
Fatigue
Frequently not defined
Rhabdomyolysis
Myopathy
Post-marketing reports
Nightmare
Polymyositis
Interstitial lung disease
Peripheral nerve palsy
Pregnancy consideration: The drug is contra-indicated in pregnant women
Pregnancy category: X
Lactation: drug is excreted in the human breast milk
Pregnancy category:
Patient information leaflet
Generic Name: pravastatin
Pronounced: pra’ va stat in
Why do we use pravastatin?
Pravastatin is used with diet to lower triglycerides and boost HDL levels (a type of fat in the blood). Low-density lipoprotein, or LDL, is the “bad” cholesterol. High-density lipoprotein, or HDL, is the “good” cholesterol.