Genomic Study Maps Shared Risk Factors for 14 Psychiatric Disorders
December 14, 2025
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Brand Name :
Vitamin B1
Synonyms :
thiamine
Class :
Vitamin B, Water soluble
Brand Name :
Vitamin B1
Synonyms :
thiamine
Class :
Vitamin B, Water soluble
Dosage Forms & Strengths
Tablet
50mg
100mg
250mg
Capsule
50mg
Injectable solution
100mg/ml
Beriberi (Thiamine Deficiency)
5-30 mg intramuscularly thrice daily if critical
Later, continue 5-30 mg thrice daily for a month
Duration depends on ongoing symptoms
100 mg intravenously; later 50-100 mg/day intramuscularly or intravenously until a regular balanced diet is consumed
Recommended Daily Allowance is:
For males- 1.2 mg/day
For females- 1.1 mg/day
During pregnancy and lactation- 1.4mg/day
Dosage Forms & Strengths
Tablet
50mg
100mg
250mg
Capsule
50mg
Injectable solution
100mg/ml
Beriberi (Thiamine Deficiency)
10-25 mg intramuscularly or intravenously each day or 10-50 mg per dose orally each day for a minimum of 2 weeks
Later, 5-10 mg/day orally for a month
Duration of treatment depends on symptoms
For 0-6 months old, 0.2 mg/day
For 6-12 months old, 0.3 mg/day
For 1-3 years old, 0.5 mg/day
For 3-8 years old, 0.6 mg/day
For 8-13 years old, 0.9 mg/day
For 13-18 years old, males, 1.2 mg/day and 1 mg/day in females
Refer to the adult dosing
lansoprazole, amoxicillin, and clarithromycin
antibiotics decrease the efficacy of thiamine by altering the gut flora
antibiotics decrease the efficacy of thiamine by altering the gut flora
antibiotics decrease the efficacy of thiamine by altering the gut flora
antibiotics decrease the efficacy of thiamine by altering the gut flora
antibiotics decrease the efficacy of thiamine by altering the gut flora
Actions and Spectrum:
Thiamine is crucial for energy production, neurotransmitter production, cell building, and cardiovascular health. It produces ATP, acetylcholine, DNA, RNA, supports nerve function, muscle contraction, and blood flow.
Frequency not defined
Anaphylaxis
Warmth
Diaphoresis
Cyanosis
Angioneurotic edema
Restlessness
Urticaria
Pruritis
Weakness
Pulmonary edema
Nausea
Throat tightness
Black Box Warning:
None
Contraindication/Caution:
Allergy & Hypersensitivity
Pregnancy consideration:
Category A
Breastfeeding warnings:
The drug is safe during lactation.
Pregnancy category:
Pharmacology:
Thiamine is for energy metabolism and nerve function absorbed in the small intestine, metabolized in the liver, distributed, and excreted in urine with supplements available for treatment.
Pharmacodynamics:
Thiamine for energy metabolism, nerve function, DNA & RNA production, cardiovascular health, and alcoholism. Its cofactor enzymes like pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase converts food into ATP. It also aids in nerve function synthesizes neurotransmitters and maintains the myelin sheath. Thiamine deficiency can lead to Wernicke-Korsakoff syndrome.
Pharmacokinetics:
Absorption
well absorbed through active transport mechanisms.
Distribution
Distributed throughout the body.
Metabolism
Metabolized in liver to its active form.
Elimination and Excretion
Excreted in urine.
Administration:
Thiamine is available in oral tablets/capsules, injectable formulations, and IV infusions.
Patient information leaflet
Generic Name: thiamine
Pronounced: thai-uh-meen
Why do we use thiamine?
Thiamine is utilized to treat thiamine deficiency, alcoholism, energy metabolism, cardiovascular and neurological health.
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