trimagnesium citrate anhydrous

Action and Spectrum

Actions and Spectrum 

Action: 

trimagnesium citrate anhydrous serves as a valuable source of magnesium when consumed, functioning primarily as a supplement for this essential mineral. magnesium plays a pivotal role in numerous biochemical processes within the body, including energy production, protein synthesis, muscle and nerve functioning, as well as the preservation of strong bones and teeth. Consequently, this medication aids in maintaining a proper magnesium intake to sustain these critical bodily functions. 

Spectrum:  

Nutritional supplementation: The drug helps to prevent or address magnesium deficiency in individuals who may have insufficient dietary intake or increased magnesium requirements 

Gastrointestinal regulation: magnesium citrate, one of the constituents of trimagnesium citrate anhydrous, has a mild laxative effect. It can help promote bowel movements and relieve occasional constipation.

Drug Interaction

Adverse Reaction

Frequency Not Defined 

Muscle weakness 

Abdominal cramping 

Hypotension 

Asthenia 

Hypermagnesemia 

Dizziness 

Electrolyte imbalance 

Respiratory depression 

Diarrhea 

Black Box Warning

Black Box Warning:  

None  

Contraindication / Caution

Contraindication/Caution:  

Allergy or hypersensitivity: Individuals with a known allergy or hypersensitivity to this drug should avoid its use. 

Kidney problems: People with severe kidney impairment or kidney failure should not use this drug unless directed by a healthcare professional.  

Bowel obstruction: If you have a known or suspected bowel obstruction, using this drug is not recommended, as it may exacerbate the condition. 

Gastrointestinal disorders: Individuals with certain gastrointestinal conditions such as inflammatory bowel disease (IBD), Crohn’s disease, or ulcerative colitis should use trimagnesium citrate anhydrous with caution and under the guidance of a healthcare professional, as it may worsen their symptoms.  

Myasthenia gravis: People with myasthenia gravis, a neuromuscular disorder characterized by muscle weakness and fatigue, should exercise caution when using trimagnesium citrate anhydrous, as it can potentially interact with medications used to manage the condition. 

Dehydration: If you are dehydrated, it is important to rehydrate before using trimagnesium citrate anhydrous, as it can further deplete fluids in the body. 

Pregnancy / Lactation

Pregnancy warnings:     

Pregnancy category: N/A 

Lactation: Excreted into human milk is unknown 

Pregnancy Categories:         

Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester. 

Category B: There were a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.   

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.    

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.    

Category N: There is no data available for the drug under this category

Pharmacology

Pharmacology:  

trimagnesium citrate anhydrous is a pharmaceutical compound with pharmacological properties primarily attributed to its magnesium and citrate components.  

Pharmacodynamics: 

The pharmacodynamics of trimagnesium citrate anhydrous involve its actions on the body. trimagnesium citrate anhydrous is a compound that contains magnesium ions bound to citrate molecules. magnesium plays a crucial role in various physiological processes in the body, including enzyme function, muscle contraction, nerve transmission, and maintaining electrolyte balance. 

When administered orally, The drug dissociates into magnesium ions and citrate molecules in the gastrointestinal tract. The magnesium ions are readily absorbed into the bloodstream and distributed throughout the body. Once in the cells, magnesium ions participate in numerous biochemical reactions and serve as cofactors for various enzymes.  

Pharmacokinetics: 

Absorption 

 The drug is generally well-absorbed in the gastrointestinal tract. magnesium ions are absorbed through both passive and active transport mechanisms in the small intestine.   

Distribution 

After being assimilated, the magnesium ions derived from trimagnesium citrate anhydrous are conveyed through the circulatory system to diverse tissues and organs. magnesium, being a vital mineral involved in multiple physiological processes, undergoes distribution throughout the entire body.  

Metabolism 

magnesium citrate does not undergo significant metabolism in the body. It remains in its intact form, and the magnesium ions are utilized by various cellular processes as needed.  

Excretion and elimination 

 The drug is primarily excreted through the kidneys via urine. excretion occurs based on the body’s magnesium balance and the regulation of magnesium levels. In cases of excessive magnesium intake, the excess is typically eliminated through urine. However, some amount of magnesium may also be excreted through feces. 

Adminstartion

Administration:  

To prepare, combine 4-8 oz of water with the product, ensuring thorough mixing before consumption.  

Patient Information Leaflet

Patient information leaflet 

Generic Name: trimagnesium citrate anhydrous 

Why do we use trimagnesium citrate anhydrous?   

Dietary Supplement: The drug is frequently employed as a magnesium source in nutritional supplements. magnesium, an indispensable mineral, assumes a critical role in numerous physiological processes such as energy generation, nerve function, muscle contraction, and maintaining optimal bone health.  

Pharmaceutical Applications: magnesium citrate, which includes trimagnesium citrate anhydrous, possesses the potential to serve as a key component in pharmaceutical formulations. Its applications range from acting as a gentle laxative for alleviating constipation to functioning as an antacid to counterbalance excessive stomach acid.  

Food Additive: The drug is sometimes added to food products as a food additive, primarily for its acidic properties. It can act as a pH regulator, antioxidant, or emulsifier in certain processed foods, beverages, and dairy products. 

Personal Care Products: magnesium citrate, including trimagnesium citrate anhydrous, can be found in some personal care products, such as toothpaste and mouthwash. It may provide benefits such as tartar control, plaque reduction, and gum health due to its antimicrobial and pH-regulating properties.