Assisted Reproductive Technology Shows Modest Impact on Childhood Immune Health
January 13, 2026
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
trimspa
Synonyms :
Trimébutine, Trimebutino, Trimebutine
Class :
Calcium Channel Blockers and Bradycardia-Causing Agents
Dosage forms & strengths
Tablets
100 mg
Spasm
It is recommended for smooth muscle relaxantion
300-600mg/day divided into 3 doses a day
N/A
Refer adult dosing
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
it increases the effect of neuromuscular blockage of neuromuscular-blocking agents
it increases the effect of neuromuscular blockage of neuromuscular-blocking agents
it increases the effect of neuromuscular blockage of neuromuscular-blocking agents
it increases the effect of neuromuscular blockage of neuromuscular-blocking agents
it increases the effect of neuromuscular blockage of neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
combining trimebutine with ipratropium may enhance the likelihood or intensity of side effects
the risk or severity of hyperkalemia may increase when isoxicam is combined with trimebutine
the use of trimebutine in combination with rimonabant increases the risk or severity of tachycardia and drowsiness
there is potential for trimebutine to enhance the neuromuscular blocking activities of tubocurarine
may decrease trimebutine elimination, raising serum levels
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
the risk of hyperkalemia may be increased
the risk of hyperkalemia may be increased
Action and spectrum:
Limited information available
Adverse effects:
Frequency not defined
Dry skin
Slow heart rate
Dilatation of pupil
Loss of accommodation
Photophobia
Black box warning:
None
Pregnancy consideration:
USFDA pregnancy category: N/A
Lactation:
unknown
Pregnancy categories:
Pharmacology:
Trimebutine affects the gastrointestinal tract by modulating gastrointestinal motility through peripheral opioid receptors. It also affects the central nervous system by regulating visceral pain perception potentially reducing discomfort associated with gastrointestinal disorders.
Pharmacokinetics
Absorption
Well absorbed
Distribution
It is widely distributed.
Metabolism
Metabolized in liver.
Excretion
Excreted through urine
Administration:
Given orally daily 3 times in divided doses.
Patient leaflet information:
Why do we use Trimebutine?
Trimebutine manages gastrointestinal disorders by reducing abdominal pain and abnormal motility. It modulates opioid receptors and blocks calcium channels making it well-tolerated.
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
