A Milestone Moment: FDA Approves Addyi® for Hypoactive Sexual Desire Disorder in Postmenopausal Women
December 17, 2025
Brand Name :
Prialt
Synonyms :
Ziconotide
Class :
Analgesic
Dosage Forms & Strengths
Intrathecal injection
25mcg/ml
100mcg/ml
2.4mcg/day intrathecal, increase up to 2.4mcg/day for 2-3 times/week
Do not exceed 19.2mcg/day
Refer adult dosing
it may increase the effects of each other
may increase the risk of sedation
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
may decrease the level by affecting hepatic enzyme CYP3A4 metabolism
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
may increase the level by affecting hepatic enzyme CYP3A4 metabolism
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
It may enhance sedation when combined with a shepherd's purse
the risk or severity of CNS depression can be increased when muzolimine is combined with ziconotide
prenylamine may amplify the arrhythmogenic activities associated with ziconotide
Frequency defined:
>10%
Ataxia
Anorexia
Abnormal gait
Diarrhea
Hypertonia
Nausea
Vomiting
Asthenia
Confusion
Hypertonia
Somnolence
Frequency not defined:
Fever
Anxiety
Speech disorder
Nervousness
Aphasia
Nervousness
Nystagmus
Pregnancy consideration: C
Lactation: The drug is excreted into the human breast milk
Pregnancy category:
Patient information leaflet
Generic Name: ziconotide
Pronounced: zye-KON-oh-tide
Why do we use ziconotide?
It is used to treat chronic pain by blocking pain signals