Chalazion

Updated: April 26, 2024

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Background

A chalazion is a benign lump that develops on the eyelid due to a blocked oil gland and it forms when the meibomian glands in the eyelid are completely blocked.

The glands produce an oily substance, but when it is blocked, the oil accumulates and forms a small lump.

Epidemiology

A chalazion is a benign lump that develops on the eyelid due to a blocked oil gland and it forms when the meibomian glands in the eyelid are completely blocked.

The glands produce an oily substance, but when it is blocked, the oil accumulates and forms a small lump.

Anatomy

Pathophysiology

Meibomian glands produce an oily substance to lubricate the eye surface and prevent tear evaporation. The blockage occurs due to thickened or hardened oil secretions.

Chalazion is formed by obstruction of the gland and sterile inflammation, which are distinct from hordeola along with the lid margin due to blockage of Zeis glands.

Etiology

The risk of developing this condition is increases due to factors such as a history of chalazion in individual, seborrheic dermatitis, and poor eyelid hygiene.

Chalazion is caused by the dysfunction of meibomian glands, which produce oily secretions that lubricate the eyes.

Genetics

Prognostic Factors

The conservative management effectively treats chalazion, with given therapy is an excellent outcome.

Chronic chalazion, which stays for an extended period, may be more difficult to treat and have a poorer prognosis compared to acute chalazion.

Clinical History

Chalazion is seen in individuals of all age groups, but it is more commonly seen in adult individuals.

Physical Examination

External inspection of eye

Assessment of vision

Assessment of Eyelid Function

Age group

Associated comorbidity

Associated activity

Acuity of presentation

In many cases it is observed that, a small and painless lump on eyelid gradually increases in size over several days or weeks.

Chalazion results in swelling that is localized to the affected eyelid. The meibomian glands are more prominent near the eyelash line or on the edge of the eyelid.

Differential Diagnoses

  • Hordeolum
  • Blepharitis
  • Sebaceous Cyst
  • Eyelid Tumor

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

Patients should apply a moist compress to their affected eyelids for 5 to 10 minutes a day.

Patients should regularly clean their eyelid margins with mild soap or cleansers to remove debris as advised by specialists only.

Eye specialists should schedule follow-up visits with patients to monitor their progress and recovery.

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

use-of-a-non-pharmacological-approach-for-chalazion

Patients should maintain good hygiene practices, especially in wound care to prevent infection.

Patients should avoid the use of harsh cosmetic products such as eye makeup removers and facial kits.

Some lifestyle modifications should be followed by patient such as intake of healthy nutritional supplements and proper hydration.

Use of Antibiotics for treatment of Chalazion

Tetracycline is used to treat chalazion which changes skin bacterial flora and produces shorter-chain fatty acids.

Doxycycline is known to inhibit protein synthesis and bacterial growth which binds to the 30S and possibly 50S ribosomal subunits of susceptible bacteria.

Use of Corticosteroids for treatment of Chalazion

Dexamethasone has anti-inflammatory properties, which binds to glucocorticoid receptors and modulates gene expression.

use-of-intervention-with-a-procedure-in-treating-chalazion

Local anesthesia is commonly used for surgical repairs of canalicular lacerations which involve topical anesthetic drops or ointment.

In the chalazion excision procedure, the chalazion is removed surgically by the surgeon after local anesthesia. This involves an incision in the eyelid and carefully removes the entire chalazion.

use-of-phases-in-managing-chalazion

In the assessment and diagnosis phase, activities like the immediate examination of patient, wound care, and pain management should be performed by the physician.

Surgical intervention is needed as per the patient’s condition and the spread of this eye condition.

In the conservative management phase, patients should receive all the required attention in the form of postoperative care, monitoring, and rehabilitation.

Provide proper education about Chalazion and its related causes, how it spreads, and how to stop it with management strategies.

Medication

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Chalazion

Updated : April 26, 2024

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A chalazion is a benign lump that develops on the eyelid due to a blocked oil gland and it forms when the meibomian glands in the eyelid are completely blocked.

The glands produce an oily substance, but when it is blocked, the oil accumulates and forms a small lump.

A chalazion is a benign lump that develops on the eyelid due to a blocked oil gland and it forms when the meibomian glands in the eyelid are completely blocked.

The glands produce an oily substance, but when it is blocked, the oil accumulates and forms a small lump.

Meibomian glands produce an oily substance to lubricate the eye surface and prevent tear evaporation. The blockage occurs due to thickened or hardened oil secretions.

Chalazion is formed by obstruction of the gland and sterile inflammation, which are distinct from hordeola along with the lid margin due to blockage of Zeis glands.

The risk of developing this condition is increases due to factors such as a history of chalazion in individual, seborrheic dermatitis, and poor eyelid hygiene.

Chalazion is caused by the dysfunction of meibomian glands, which produce oily secretions that lubricate the eyes.

The conservative management effectively treats chalazion, with given therapy is an excellent outcome.

Chronic chalazion, which stays for an extended period, may be more difficult to treat and have a poorer prognosis compared to acute chalazion.

Chalazion is seen in individuals of all age groups, but it is more commonly seen in adult individuals.

External inspection of eye

Assessment of vision

Assessment of Eyelid Function

In many cases it is observed that, a small and painless lump on eyelid gradually increases in size over several days or weeks.

Chalazion results in swelling that is localized to the affected eyelid. The meibomian glands are more prominent near the eyelash line or on the edge of the eyelid.

  • Hordeolum
  • Blepharitis
  • Sebaceous Cyst
  • Eyelid Tumor

Patients should apply a moist compress to their affected eyelids for 5 to 10 minutes a day.

Patients should regularly clean their eyelid margins with mild soap or cleansers to remove debris as advised by specialists only.

Eye specialists should schedule follow-up visits with patients to monitor their progress and recovery.

Ophthalmology

Patients should maintain good hygiene practices, especially in wound care to prevent infection.

Patients should avoid the use of harsh cosmetic products such as eye makeup removers and facial kits.

Some lifestyle modifications should be followed by patient such as intake of healthy nutritional supplements and proper hydration.

Ophthalmology

Tetracycline is used to treat chalazion which changes skin bacterial flora and produces shorter-chain fatty acids.

Doxycycline is known to inhibit protein synthesis and bacterial growth which binds to the 30S and possibly 50S ribosomal subunits of susceptible bacteria.

Ophthalmology

Dexamethasone has anti-inflammatory properties, which binds to glucocorticoid receptors and modulates gene expression.

Ophthalmology

Local anesthesia is commonly used for surgical repairs of canalicular lacerations which involve topical anesthetic drops or ointment.

In the chalazion excision procedure, the chalazion is removed surgically by the surgeon after local anesthesia. This involves an incision in the eyelid and carefully removes the entire chalazion.

Ophthalmology

In the assessment and diagnosis phase, activities like the immediate examination of patient, wound care, and pain management should be performed by the physician.

Surgical intervention is needed as per the patient’s condition and the spread of this eye condition.

In the conservative management phase, patients should receive all the required attention in the form of postoperative care, monitoring, and rehabilitation.

Provide proper education about Chalazion and its related causes, how it spreads, and how to stop it with management strategies.

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