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Lymphogranuloma Venereum

Updated : June 27, 2022





Background

Lymphogranuloma venereum is an ulcerative condition which affects the genital region. The gram-negative bacteria Chlamydia trachomatis, and serovars L1, L2, and L3, are the cause of this condition.

This is a rare sexually transmitted disease. It can be transmitted by oral, vaginal and anal intercourse. Many reports indicate the prevalence of this disease in actively homosexual males.

Epidemiology

LGV is prevalent in the world’s subtropical and tropical climates. This is uncommon in the US. Lymphogranuloma venereum can affect anyone at any age; but, the peak frequency of Lymphogranuloma venereum is noticeable between the ages of 15-40 in the population which is sexually active.

Lymphogranuloma venereum presumably equally affects both male and females, albeit it is recorded more frequently in men due to the fact that early signs of Lymphogranuloma venereum are more prevalent in men.

It is prevalent among guys who have intercourse with other men. A strong correlation exists between HIV-positive people and LGV. Typically, men are observed to be infected with the acute phase of this disease, and women are diagnosed in the later stages.

Anatomy

Pathophysiology

The lymphatic system is largely affected by lymphogranuloma venereum. The attachment of Chlamydia trachomatis to epithelial cells facilitates the spread of Chlamydia trachomatis serovars from the initial site of infection to regional lymph nodes and the subsequent lymphoproliferative response. The binding happens through heparin sulphate receptors.

Etiology

This disease is caused by Chlamydia trachomatis, and serovars L1, L2, and L3

Genetics

Prognostic Factors

If the disease is found early, is has a good prognosis.

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

Media Gallary

References

https://www.ncbi.nlm.nih.gov/books/NBK537362/

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Lymphogranuloma Venereum

Updated : June 27, 2022




Lymphogranuloma venereum is an ulcerative condition which affects the genital region. The gram-negative bacteria Chlamydia trachomatis, and serovars L1, L2, and L3, are the cause of this condition.

This is a rare sexually transmitted disease. It can be transmitted by oral, vaginal and anal intercourse. Many reports indicate the prevalence of this disease in actively homosexual males.

LGV is prevalent in the world’s subtropical and tropical climates. This is uncommon in the US. Lymphogranuloma venereum can affect anyone at any age; but, the peak frequency of Lymphogranuloma venereum is noticeable between the ages of 15-40 in the population which is sexually active.

Lymphogranuloma venereum presumably equally affects both male and females, albeit it is recorded more frequently in men due to the fact that early signs of Lymphogranuloma venereum are more prevalent in men.

It is prevalent among guys who have intercourse with other men. A strong correlation exists between HIV-positive people and LGV. Typically, men are observed to be infected with the acute phase of this disease, and women are diagnosed in the later stages.

The lymphatic system is largely affected by lymphogranuloma venereum. The attachment of Chlamydia trachomatis to epithelial cells facilitates the spread of Chlamydia trachomatis serovars from the initial site of infection to regional lymph nodes and the subsequent lymphoproliferative response. The binding happens through heparin sulphate receptors.

This disease is caused by Chlamydia trachomatis, and serovars L1, L2, and L3

If the disease is found early, is has a good prognosis.

https://www.ncbi.nlm.nih.gov/books/NBK537362/

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