Testicular cancer

Updated: July 12, 2022

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Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

 

vinblastine

6

mg/m^2

Intravenous (IV)

once a day

2

days

for every 3 to 4 weeks with apart of combination treatment



etoposide

for testicular cancer the etoposide and combination with other agents used as a dose :

50 - 100

mg/m^2

Intravenous (IV)

30-60 minutes once a day from days 1-5 every 3-4 weeks to 100 mg per m2 IV over 30-60 minutes once a day from days 1-5 every 3-4 weeks



dactinomycin

Therapy duration 12 weeks:

1000

mcg/m^2

Intravenous (IV)

every 3 weeks

in combination with cisplatin and other chemotherapeutic agents.



plicamycin

It is used for malignant tumors of the testis where the treatment by surgery/radiation is unsuccessful :

25 - 30

mcg

or 0.025-0.030 mg/kg
Continue the treatment for 8-10 days until disease progression or unacceptable toxicity occurs
Therapy should not exceed more than ten daily doses
The individual daily dose should not exceed 0.030 mg/kg



ifosfamide 

Administer dose of 1.2 g/m² daily through intravenous infusion over 30 minutes on day number 1 to 5 for every 3 to 4 weeks



 

vinblastine

When vinblastine alone without combination with other drugs given, the initial dose :

6.5

mg/m^2

Intravenous (IV)

When used in combination with other drugs given, the initial dose of 6.5 mg per m2 IV



 

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References

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Testicular cancer

Updated : July 12, 2022
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