Genomic Study Maps Shared Risk Factors for 14 Psychiatric Disorders
December 14, 2025
Brand Name :
Differin
Synonyms :
Class :
Acne agents; Retinoids
Dosage forms & Strengths:
Adult:
Topical cream:
0.1%
Topical gel:
0.1%
0.3%
Topical lotion:
0.1%
Indicated as topical administration for acne vulgaris
After washing the face, apply the dosage form as a thin film on the affected area of the skin every evening
A warm sensation may occur on the skin after applying the same
In case of apparent worsening, do not discontinue the treatment
Apply the dosage form as a film on the affected area of the skin every evening
Not for children below 12 years
drospirenone/ethinyl estradiol/levomefolate
may diminish the therapeutic effect of progestins
may increase the adverse effect of Multivitamins/Fluoride
it increases the toxicity of retinoic acid derivatives
It may enhance the risk of adverse effects when combined with oxazolidinones
It may enhance the risk of adverse effects when combined with oxazolidinones
bismuth subcitrate, metronidazole and tetracycline
may enhance the risk of adverse effect of retinoic acid derivatives
may enhance the risk of adverse effect of retinoic acid derivatives
may enhance the risk of adverse effect of retinoic acid derivatives
may enhance the risk of adverse effect of retinoic acid derivatives
may enhance the risk of adverse effect of retinoic acid derivatives
may increase the risk of adverse effects
l-methylfolate-pyridoxal 5′-phosphate-methylcobalamine
may increase the risk of adverse effects
bismuth subcitrate, metronidazole and tetracycline
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may enhance the adverse/toxic effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
retinoic acid derivatives decrease the efficacy of progestins
retinoic acid derivatives decrease the efficacy of progestins
retinoic acid derivatives decrease the efficacy of progestins
retinoic acid derivatives decrease the efficacy of progestins
retinoic acid derivatives decrease the efficacy of progestins
retinoic acid derivatives decrease the efficacy of progestins
>10%:
Dryness
Scaling
Burning/stinging
Erythema
1-10%:
Skin discomfort
Pruritus
Desquamation
Sunburn
<1%:
Acne flare
Conjunctivitis
Contact dermatitis
Eczema
Erythema
Eyelid edema
Rash
Skin discoloration
Adapalene is contraindicated in people hypersensitive to adapalene.
Pregnancy consideration:
Data obtained from clinical trials are insufficient.
Breastfeeding warnings:
Breastfeeding should be performed with caution, utilizing a limited area.
Pregnancy category:
Patient information leaflet
Generic Name: adapalene
Pronounced: a-DAP-a-leen
Why do we use adapalene?
Adapalene treats acne vulgaris.