Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
GenESA
Synonyms :
arbutamine
Class :
Adrenergic beta-receptor agonists, Cardiotonic Agents
Brand Name :
GenESA
Synonyms :
arbutamine
Class :
Adrenergic beta-receptor agonists, Cardiotonic Agents
Dosage Forms & Strengths
Injectable solution
0.05 mg/ml
Arbutamine is a synthetic catecholamine used in diagnostic coronary angiography and echocardiography that has positive chronotropic and inotropic properties
Not determined
Refer to adult dosing
may increase the risk of hypertension when combined
When used with levobetaxolol, arbutamine's therapeutic effectiveness may be diminished
arbutamine: it may decreased the serum concentration of CNS depressants
arbutamine: it may decreased the serum concentration of CNS depressants
arbutamine: it may decreased the serum concentration of CNS depressants
arbutamine: it may decreased the serum concentration of CNS depressants
arbutamine: it may decreased the serum concentration of CNS depressants
When arbutamine is used together with diazoxide, this leads to reduction in diazoxide’s antihypertensive effects
may increase the risk or severity of adverse effects when combined
may increase the risk or severity of hypertension when combined
the risk of hypertension may be increased
the risk of hypertension may be increased
Actions and Spectrum
Arbutamine stimulates beta-1 adrenergic receptors, which are predominantly located in the heart.
This results in increased heart rate, increased contractility, and increased conductivity.
Frequency not defined
None
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
Arbutamine exhibits more selectivity for beta-1 receptors compared to beta-2 receptors.
Beta-1 receptors are found in the heart, while beta-2 receptors are more prevalent in the lungs and other tissues.
Pharmacodynamics
Arbutamine increases heart rate by acting on the sinoatrial node, which enhances the rate of pacemaker activity.
The drug enhances myocardial contractility, leading to increased force of cardiac contractions.
Pharmacokinetics
Limited information available on ADME.
Administration
Arbutamine is administered intravenously.
Patient information leaflet
Generic Name: arbutamine
Why do we use arbutamine?
Arbutamine is indicated to induce stress during echocardiography, a non-invasive imaging technique that uses ultrasound to visualize the heart.
Arbutamine is used to identify signs of coronary artery disease (CAD) by assessing the heart’s response to stress.
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