A Milestone Moment: FDA Approves Addyi® for Hypoactive Sexual Desire Disorder in Postmenopausal Women
December 17, 2025
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Brand Name :
Xeloda
Synonyms :
Class :
Antineoplastics; Antimetabolite
Brand Name :
Xeloda
Synonyms :
Class :
Antineoplastics; Antimetabolite
Dosage forms & Strengths:
Adult:
Tablet:
150 mg
500 mg
Capsule:
250 mg
500 mg
Safety and efficacy not established
capecitabine: it may increase the risk of methemoglobinemia agents
capecitabine: it may increase the risk of methemoglobinemia agents
capecitabine: it may increase the risk of methemoglobinemia agents
capecitabine: it may increase the risk of methemoglobinemia agents
capecitabine: it may increase the risk of methemoglobinemia agents
It may increase the nephrotoxic effect when combined with Bisphosphonate Derivatives
It may increase the nephrotoxic effect when combined with Bisphosphonate Derivatives
It may increase the nephrotoxic effect when combined with Bisphosphonate Derivatives
It may increase the nephrotoxic effect when combined with Bisphosphonate Derivatives
It may increase the nephrotoxic effect when combined with Bisphosphonate Derivatives
capecitabine together with cisapride lead to an elevation of the QTc interval
When capecitabine is used together with fluconazole, this leads to reduction in the capecitabine metabolism
When mometasone furoate is used together with capecitabine, this leads to enhanced risk or seriousness of adverse outcomes
When capecitabine is used together with andrographolide, this leads to enhanced risk or seriousness of bleeding
capecitabine leads to a reduction in the rate of excretion of eucalyptus oil which leads to increased level of serum
capecitabine leads to a reduction in the rate of excretion of pentaerythritol tetranitrate, which leads to an increased level of serum
capecitabine leads to a reduction in the rate of excretion of potassium acetate, which leads to an increased level of serum
capecitabine leads to a reduction in the rate of excretion of potassium perchlorate, which leads to an increased level of serum
capecitabine may decrease the excretion rate of almasilate, leading to higher serum levels
when both drugs are combined, there may be an increased risk or severity of adverse effects
may increase the level by affecting hepatic enzyme CYP2C9 metabolism
telotristat ethyl: they may diminish serum concentrations of capecitabine
capecitabine might lead to a reduction in the rate of excretion of telavancin, potentially leading to elevated levels of serum
>10%:
Diarrhea
Nausea
Anemia
Lymphopenia
Hand and foot syndrome
Edema
Fatigue
Fever
Headache
Pain
Alopecia
Dyspepsia
Stomatitis
Thrombocytopenia
Dermatitis
Abdominal pain
Anorexia
Appetite decreased
Vomiting
Paresthesia
Neutropenia
Dyspnea
Bilirubin increased
Eye irritation
1-10%:
Chest pain
Pruritus
Rash
Taste disturbance
Dehydration
Dizziness
Headache
Weakness
Dermatitis
Dry mouth
Dyspepsia
Back pain
Pregnancy consideration:
The drug is not recommended during pregnancy
Breastfeeding warnings:
Unknown
Pregnancy category:
Patient information leaflet
Generic Name: capecitabine
Pronounced: kape-cita-bine
Why do we use capecitabine?
Capecitabine treats colorectal and breast cancer.
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