- March 15, 2022
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Brand Name :
APO-Cefprozil, Auro-Cefprozil, SANDOZ Cefprozil, Taro-Cefprozil
Synonyms :
Class :
Antibiotics & Cephalosporins (second generation)
Dosage forms & Strengths
Tablet, Oral
250 mg
500 mg
Suspension, Oral:
125 mg/5ml (150ml)
250 mg/5ml (150ml)
Acute bacterial chronic bronchitis:
500 mg q12 hours for 10 days
Pharyngitis/tonsillitis:
500 mg q24 hours for 10 days
Administer for more than 10 days if S.pyogenes infection
Skin infections:
500 mg q24 hours for 10 days, > 10 days for S.pyogenes infection
Dose adjustments:
CrCl > 30 ml/minute: No dosage adjustment indicated
CrCl < 30 ml/minute: Administer 50% of the dose
For end-stage renal disease (ESRD): Administer dose only after dialysis
CrCl > 50 ml/minute: No dosage adjustment indicated
CrCl <50 ml/minute: Administer 50% of the dose every 12 hours
No dosage adjustment indicated for hepatic impairment
500
mg
Orally
every 12 hrs
10
days
Tablet
500
mg
Orally
every 24 hours
10
days
Tablet
If the infection is caused by S. pyrogenes, administer the dose for more than 10 days
500
mg
Orally
every 24 hours
10
days
Tablet
Dosage forms & Strengths
Tablet, Oral
250 mg
500 mg
Suspension, Oral:
125 mg/5ml (150ml)
250 mg/5ml (150ml)
General dosing indication for infants, children, and adolescents with mild to moderate infection:
7.5-15 mg/kg b.i.d q12 hours (do not exceed 500 mg /dose)
Chronic bronchitis:
Adolescents: 500 mg q12 hours for 10 days
Acute otitis media:
Infants > 6 months and children: 15 mg/kg b.i.d for 10 days q12 hours (do not exceed 500 mg/dose)
Not recommended as routine treatment
Pharyngitis:
Children >2 years: 7.5 mg/kg b.i.d for 10 days q12 hours (do not exceed 500 mg/dose)
Adolescents: 500 mg q24 hours for 10 days
Rhinosinusitis:
Infants > 6 months and children: 7.5-15 mg/kg b.i.d for 10 days q12 hours (do not exceed 500 mg/dose)
Adolescents: 250-500 mg b.i.d for 10 days q12hours
Skin infections:
Children > 2 years: 20 mg/kg per dose QD for 10 days (do not exceed 500 mg/dose)
Adolescents: 250 mg q12hours for 10 days
Urinary tract infection:
Infants > 2 months to children < 2 years: 15 mg/kg b.i.d for 7 to 14 days
Dose adjustments:
CrCl > 30 ml/minute: No dosage adjustment indicated
CrCl < 30 ml/minute: Administer 50% of the dose
For end-stage renal disease (ESRD): Administer dose only after dialysis
7.5
mg/kg
Orally
twice a day
10
days
Tablet
Do not exceed 500 mg/dose
20
mg/kg
Orally
4 times a day
10
days
Tablet
Do not exceed 500 mg/dose
15
mg/kg
Orally
twice a day
7 - 14
days
Tablet
Refer to adult dosing
the interaction decreases the therapeutic effects of the vaccine
the interaction decreases the therapeutic effects of the vaccine
the interaction decreases the therapeutic effects of the vaccine
bazedoxifene conjugated estrogens
cefprozil may reduce the therapeutic effects of oral forms of conjugated estrogen by altering gut microflora
cefprozil will reduce the therapeutic effects of oral forms of hormones by altering gut microflora
cefprozil will reduce the therapeutic effects of oral forms of hormones by altering gut microflora
furosemide may enhance the therapeutic effects of cefprozil
the interaction may increase the therapeutic effects of cefprozil
the interaction may increase the therapeutic effects of cefprozil
cefprozil reduces the therapeutic effects of sodium picosulfate by altering metabolism
cephalosporins may decrease serum concentration and enhance nephrotoxicity of aminoglycosides
enhance the serum drug concentration by reducing renal clearance
enhance the serum drug concentration by reducing renal clearance
may raise the risk of nephrotoxicity
cefprozil increases the anticoagulant activity of warfarin by an unknown mechanism
it may diminish the excretion rate when combined with estradiol valerate resulting in a greater serum level
cefprozil has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefprozil increases the serum concentration of other drugs by reducing renal clearance
cefprozil increases the serum concentration of other drugs by reducing renal clearance
cefprozil increases the serum concentration of other drugs by reducing
the interaction reduces the effects of cefprozil
cefprozil increases the therapeutic effects of cyclopenthiazide
cefprozil will increase the effects of sulfasalazine
Frequency defined:
1% to 10%:
Dizziness (1%)
Rashes (2%)
Pruritis (2%)
Nausea
Vomiting
Abdominal pain
<1%:
Confusion
Drowsiness
Eosinophilia
Fever
Insomnia
Serum sickness
Thrombocytopenia
Increased serum creatinine
Pregnancy consideration: Cefprozil is assigned under pregnancy category B. No adverse effects were observed in animal studies.
Lactation: Use with caution for breastfeeding females as it can be excreted in a small amount in breast milk.
Pregnancy category:
Patient information leaflet
Generic Name: Cefprozil
Pronounced: sef-pro-zil
Why do we use cefaclor?
Cefprozil is a second-generation cephalosporin antibiotic drug. It is used to treat bacterial infections, which kill bacteria by inhibiting bacterial cell wall synthesis.
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Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
MASSACHUSETTS – USA
60 Roberts Drive, Suite 313,
North Adams, MA 01247
MAHARASHTRA – INDIA
7, Shree Krishna, 2nd Floor,
Opp Kiosk Koffee,
Shirole Lane, Off FC Road,
Pune 411004, Maharashtra
