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Brand Name :
N/A
Synonyms :
DL-Methylephedrine
Class :
Sympathomimetic amine
Dosage Forms & Strengths
Capsule
N/A
DL-Methylephedrine is approved drug and it is indicated in the treatment of respiratory conditions such as asthma or bronchitis
N/A
Refer to adult dosing
may decrease the therapeutic effects
spironolactone and hydrochlorothiazide
It may enhance the risk of bleeding when combined with Decongestants
It may enhance the risk of bleeding when combined with Decongestants
It may enhance the risk of bleeding when combined with Decongestants
It may enhance the risk of bleeding when combined with Decongestants
It may enhance the risk of bleeding when combined with Decongestants
It may enhance the risk of adverse effects when combined with Decongestant
It may enhance the risk of adverse effects when combined with Decongestant
decongestant: they may increase the hypertensive effect of Alpha 2-Agonists
decongestant: they may increase the hypertensive effect of Alpha 2-Agonists
decongestant: they may increase the hypertensive effect of Alpha 2-Agonists
decongestant: they may increase the hypertensive effect of Alpha 2-Agonists
decongestant: they may increase the hypertensive effect of Alpha 2-Agonists
may diminish the serum concentration
spironolactone and hydrochlorothiazide
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
It may enhance the risk of nephrotoxicity when combined with Dopamine agonists
It may enhance the risk of nephrotoxicity when combined with Dopamine agonists
It may enhance the risk of nephrotoxicity when combined with Dopamine agonists
It may enhance the risk of nephrotoxicity when combined with Dopamine agonists
It may enhance the risk of nephrotoxicity when combined with Dopamine agonists
Actions and Spectrum
DL-Methylephedrine stimulates both alpha- and beta-adrenergic receptors. Activation of these receptors leads to effects such as increased heart rate, increased blood pressure, and bronchodilation.
DL-Methylephedrine has vasoconstrictive properties, which means it can constrict blood vessels. This action can reduce nasal congestion by decreasing blood flow to the nasal mucosa.
Frequency not defined
None
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
DL-Methylephedrine has vasoconstrictive effects which causes constriction of blood vessels. This property is responsible for its use as a nasal decongestant by reducing blood flow to nasal mucosa.
Pharmacodynamics
Stimulation of beta1-adrenergic receptors in the heart increases heart rate and contractility.
Stimulation of beta2-adrenergic receptors in the bronchi promotes bronchodilation.
Pharmacokinetics
Absorption
DL-Methylephedrine is absorbed from the gastrointestinal tract into the bloodstream.
Distribution
DL-Methylephedrine can distribute to various tissues.
Metabolism
DL-Methylephedrine undergoes metabolism in the liver.
Elimination and excretion
DL-Methylephedrine is excreted from the body through renal route.
Administration
DL-Methylephedrine is available in oral capsule and liquid forms.
Patient information leaflet
Generic Name: DL-Methylephedrine
Why do we use DL-Methylephedrine?
DL-Methylephedrine has vasoconstrictive properties, used to reduce the blood flow to the nasal mucosa.
DL-Methylephedrine is used as a bronchodilator, in the treatment of respiratory conditions such as asthma or bronchitis.