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Brand Name :
Potiga
Synonyms :
ezogabine
Class :
Anticonvulsants
Dosage Forms & Strengths Â
Tablet Â
50mg Â
200mg Â
300mg Â
400mg Â
100
mg
Orally 
every 8 hrs
a day 1 week; titrate and increase for 50 mg orally
Maintenance dose: 200 mg-400 mg orally 8 hours a day
Do not exceed 400 mg a day
QTc interval is increased both by lenvatinib and ezogabine
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
When ezogabine is used together with adenine, this leads to a reduction in the ezogabine’s metabolism
when both drugs are combined, there may be an increased risk or severity of adverse effects  
Adverse drug reactions Â
Frequency Defined Â
>10% Â
Somnolence (22%) Â
Dizziness (23%) Â
Fatigue (15%) Â
1-10% Â
Tremor (8%) Â
Nausea (7%) Â
Attention disturbance (6%) Â
Memory impairment (6%) Â
Confusion (9%) Â
Vertigo (8%) Â
Abnormal coordination (7%) Â
Diplopia (7%) Â
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Pregnancy warnings:   
AU TGA pregnancy category: CÂ
Lactation: Â
Excreted into human milk is unknown Â
Pregnancy Categories:       Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.  Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were no enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this category Â
Patient Information Leaflet   Â
Generic Name: ezogabineÂ
Why do we use ezogabine? Â
ezogabine is an Anticonvulsants used to treat Partial Onset Seizures.Â