Long COVID Patterns in the RECOVER-Adult Study
November 21, 2025
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Brand Name :
N/A
Synonyms :
8 (S)-fluoro-erythromycin, fluritromicina
Class :
Macrolide antibiotic/second generation
Brand Name :
N/A
Synonyms :
8 (S)-fluoro-erythromycin, fluritromicina
Class :
Macrolide antibiotic/second generation
Dosage Forms & StrengthsÂ
TabletÂ
375mgÂ
Lower Respiratory Tract InfectionsÂ
375
mg
Tablets
Orally 
twice a day
2
weeks
Dose Adjustments
Off-label
Data not availableÂ
Refer to adult dosingÂ
the serum levels of abemaciclib may be increased
the serum levels of acetyldigitoxin may be increased
the rate of metabolism of albendazole may be reduced
the serum levels of alectinib may be increased
the serum levels of alfentanil may be increased
the serum levels of alpelisib may be increased
the serum levels of alprazolam may be increased
the risk of methemoglobinemia may be increased
the serum levels of amiodarone may be increased
the rate of metabolism of aripiprazole may be reduced
the rate of metabolism of aripiprazole lauroxil may be reduced
the risk of methemoglobinemia may be increased
the therapeutic efficacy of BCG vaccine may be reduced
the risk of methemoglobinemia may be increased
the risk of methemoglobinemia may be increased
the serum levels of bortezomib may be increased
the serum levels of brentuximab vedotin may be increased
the risk of methemoglobinemia may be increased
the serum levels of cabergoline may be increased
the risk of methemoglobinemia may be increased
the rate of metabolism of cephalexin may be reduced
the risk of methemoglobinemia may be increased
the rate of metabolism of cilostazol may be reduced
the risk of methemoglobinemia may be increased
the rate of metabolism of cyclosporine may be reduced
the serum levels of deflazacort may be increased
Actions and spectrum:Â
Actions:Â
Flurithromycin is an antibiotic of the class macrolides. It binds to the 50S subunit of ribosomes and prevents the protein synthesis in bacteria.Â
Spectrum of activity:Â
It’s a broad-spectrum antibiotic that works similarly to erythromycin in terms of bactericidal action. In contrast to erythromycin, flurithromycin exhibits more excellent resistance to acidic environments. This means that a more significant amount of the drug survives the digestive process, leading to elevated serum levels and more effective eradication of susceptible bacteria, such as Streptococcus pyogenes and Staphylococcus aureus.Â
Frequency not definedÂ
The list of adverse reactions is not documentedÂ
Black Box Warning Â
No special warnings are available for this drugÂ
Contraindication/Caution:Â
Contraindication:Â
CardiotoxicityÂ
Alopecia Â
Pregnancy consideration:Â Â
USFDA pregnancy category: Not assignedÂ
Lactation:Â Â
Data about the excretion of flurithromycin into breast milk is not knownÂ
Pregnancy category:Â Â
Category A: Studies that were well-controlled and met expectations revealed no risk to the foetus in either the first or second trimester.Â
Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.  Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.  Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this category
Pharmacology:Â
Flurithromycin is an antibacterial agent and a derivative of erythromycin. It can also be isolated from Streptomyces erythraeus.Â
Pharmacodynamics:Â
Fluorination of erythromycin at the C-8 position yields flurithromycin to be stable in acidic environments. It is known to produce antibacterial activity by preventing bacterial protein synthesis as it binds to 50S subunits of ribosomesÂ
Pharmacokinetics:Â
The data about the pharmacokinetic study of flurithromycin is not availableÂ
Administration:Â
Flurithromycin is to be taken orally after mealsÂ
Patient information leafletÂ
Generic Name: flurithromycin Â
Why do we use flurithromycin?Â
Flurithromycin is a second-generation macrolide antibiotic like erythromycin, dirithromycin, azithromycin, roxithromycin, and clarithromycin. It is used in the treatment of infections of the upper and lower respiratory tract.Â
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