glycol salicylate

Action and Spectrum

Actions and Spectrum: 

glycol salicylate works as a counterirritant, temporarily relieving minor aches and pains associated with muscle strains, sprains, and arthritis. Applying it to the skin produces a warming sensation and distracts from the underlying pain. It has mild anti-inflammatory properties, which can help reduce localized inflammation in the application area. 

Drug Interaction

Adverse Reaction

Frequency not defined 

Renal failure 

Hypertension 

Hyperkalemia 

Black Box Warning

Black Box Warning: 

None

Contraindication / Caution

Contraindication/Caution: 

Contraindications: 

• Allergy or Hypersensitivity 
• Children and Infants 
• Aspirin Sensitivity 

Cautions: 

• Skin Irritation and Sensitivity: glycol salicylate can cause skin irritation, mainly when applied to broken or damaged skin. Individuals with sensitive skin should use such products cautiously and discontinue use if irritation occurs. 
• Avoid Eye and Mucous Membrane Contact: glycol salicylate-containing products should not be applied near the eyes or on mucous membranes (e.g., inside the nose or mouth). 
• Pregnancy and Breastfeeding: The safety of glycol salicylate use during pregnancy and breastfeeding is not well-established. Pregnant or breastfeeding individuals should consult a healthcare professional before using such products. 
• Use on Large Areas or Prolonged Use: Excessive or prolonged use of glycol salicylate-containing products on large body areas can increase the risk of systemic absorption and potential toxicity. 

Pregnancy / Lactation

Pregnancy consideration:  

No data is available  

Breastfeeding warnings:  

No data is available 

Pregnancy category: 

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester. 
• Category B: No evidence of risk to the fetus is found in animal reproduction studies, and there are not enough studies on pregnant women. 
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a human product; Pregnant women must take care of the potential risks. 
• Category D: There is adequate data with sufficient evidence of human fetal risk from various platforms. However, despite potential dangers may be used only in emergencies for potential benefits. 
• Category X: Drugs listed in this category outweigh the risks over benefits. The drug is not for pregnant women. 
• Category N: No data for the drug under this category is available. 

Pharmacology

Pharmacology: 

• Indication: The product is indicated to relieve minor to moderate aches and pains temporarily. 
• Ingredients: The product contains ingredients such as menthol, a common counter-irritant known for its cooling sensation. 
• Counter-Irritant Properties: Counter-irritants are applied externally to the skin and cause mild irritation or inflammation to reduce pain in muscles or joints. 

Pharmacodynamics: 

• Vasodilation and Heat Sensation: Counter-irritants may cause vasodilation (widening of blood vessels) or skin irritation that causes a false sensation of heat or warmth in the affected area. 
• Duration of Relief: The relief provided by counter-irritants is usually temporary and may vary based on the individual and the severity of the pain. 

Pharmacokinetics: 

No pharmacokinetic studies have been performed yet.

Adminstartion

Administration: 

glycol salicylate is a topical patch to relieve muscle aches and stiffness. 

Patient Information Leaflet

Patient information leaflet 

Generic Name:  glycol salicylate 

Pronounced: gly-kol sal-i-ci-late 

Why do we use glycol salicylate? 

glycol salicylate is thought to be used as a counterirritant to relieve muscle aches and stiffness.