Impact of High-Pillow Sleeping Posture on Intraocular Pressure in Glaucoma
January 28, 2026
Brand Name :
Zurampic (DSC)
Synonyms :
lesinurad
Class :
Antigout Agent; Uric Acid Transporter Inhibitor
Safety and efficacy are not seen in pediatrics
Safety and efficacy are not seen in pediatrics
CYP2C9 enhancers may decrease the the bioavailability of lesinurad
valproate products increase the concentration of lesinurad in serum
It may enhance the adverse effects when combined with pegloticase
when both drugs are combined, there may be a decreased level of serum concentration of lesinurad
the effect of lesinurad is increased by fluorouracil by the action on CYP2C9/10 hepatic enzyme metabolism
may enhance the serum concentration of CYP2C9 inhibitors
>10%:
Dizziness
Dry mouth
Nausea
Somnolence
Tachycardia
1-10%:
Ejaculation failure
Diarrhea
Myalgia
Palpitations
Nasal congestion
Weight gain
Urinary incontinence
<1%:
Edema
Amenorrhea
Hypothyroidism
Frequency undefined:
Priapism
Lesinurad is contraindicated in patients hypersensitive to the active ingredient.
Pregnancy consideration:
Category C
Breastfeeding warnings:
No data is available regarding the excretion of the drug in breast milk.
Pregnancy category:
Patient information leaflet
Generic Name: lesinurad
Pronounced: le-sin-ure-ad
Why do we use:
Lesinurad is an antigout agent. It is used to treat hyperuricemia.