Brand Name :
Depacon
Synonyms :
valproate sodium injection
Class :
Anticonvulsants; Antiepileptic agents
Dosage forms & Strengths
IV solution (as valproate sodium)
100mg/mL
Indicated for Complex Partial Seizures
10-15 mg/kg IV divided 2 times a day infused over 1 hour
May be increased to 60 mg/kg daily
Maximum duration is 14 days (AS soon as possible switch to Oral)
Dosage forms & Strengths
IV solution (as valproate sodium)
100mg/mL
Indicated for Complex Partial Seizures
10-15 mg/kg IV divided 2 times a day infused over 1 hour
May be increased to 60 mg/kg daily
Maximum duration is 14 days (AS soon as possible switch to Oral)
Refer adult dosing
valproate products increase the concentration of lesinurad in serum
may have an increased hepatotoxic effect when combined with valproate products
valproate increases the concentration of serum barbiturates in the serum
valproate increases the concentration of serum barbiturates in the serum
valproate increases the concentration of serum barbiturates in the serum
valproate increases the concentration of serum barbiturates in the serum
valproate increases the concentration of serum barbiturates in the serum
valproate increases the hepatotoxicity of cannabidiol
it increases the effect of CNS depressants
valproate decreases the efficacy of apixaban
valproate increases the toxicity of bupivacaine
may enhance the serum concentration
it increases the concentration of valproate products in the serum
valproate products increase the CNS depressing effect of clobazam
valproate products decrease the efficacy of dabigatran etexilate
it decreases the concentration of valproate products in the serum
valproate products increase the concentration of rufinamide in serum
Frequency defined
10%
Alopecia
Thrombocytopenia
Infection
Dizziness
Nausea
Dyspepsia
Pain
Tremor
Asthenia
Flu-like symptoms
1-10%:
Cardiac arrhythmia
Edema
Hypertension
Hypotension
Tachycardia
Amenorrhea
Weight loss
Constipation
Fecal incontinence
Fungal infection
<1%:
Inflammation
Euphoria
Hypoesthesia
Vasodilation
Pharyngitis
Valproate is contraindicated in patients hypersensitive to the formulation’s active ingredient and other excipients.
Pregnancy consideration:
Valproate crosses the placental barrier, hence should not be used in pregnancy
Breastfeeding warnings:
The valproate is secreted in breastmilk
Pregnancy category:
Patient information leaflet
Generic Name: valproate sodium injection
Why do we use valproate sodium injection?
valproate sodium injection is used for various medical purposes. Here are some common reasons for its use:
Treatment of seizures: valproate sodium injection is primarily used in the management of seizures or epilepsy. It can be particularly effective in controlling absence seizures, generalized tonic-clonic seizures, and complex partial seizures.
Acute manic or mixed episodes associated with bipolar disorder: Valproate sodium injection may be used in the treatment of acute manic or mixed episodes associated with bipolar disorder. It can help stabilize mood and reduce symptoms such as irritability, impulsivity, and elevated mood.
Migraine prophylaxis: valproate sodium injection is sometimes utilized for the prevention of migraine headaches.
ADVERTISEMENT
Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
USA – BOSTON
60 Roberts Drive, Suite 313
North Adams, MA 01247
INDIA – PUNE
7, Shree Krishna, 2nd Floor, Opp Kiosk Koffee, Shirole Lane, Off FC Road, Pune 411004, Maharashtra
Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
MASSACHUSETTS – USA
60 Roberts Drive, Suite 313,
North Adams, MA 01247
MAHARASHTRA – INDIA
7, Shree Krishna, 2nd Floor,
Opp Kiosk Koffee,
Shirole Lane, Off FC Road,
Pune 411004, Maharashtra
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
