Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Lorflex Plus, Flexilor-P, Mitilor, Lornoxi-P, Lonax, Lorsaid, Flexilor, Lornigesic, Noxi, Lirnor, Lorwalk, Camri, Mitilor, Flexilor, Neucam, Zelorn, Lornistar-P
Synonyms :
lornoxicam
Class :
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Brand Name :
Lorflex Plus, Flexilor-P, Mitilor, Lornoxi-P, Lonax, Lorsaid, Flexilor, Lornigesic, Noxi, Lirnor, Lorwalk, Camri, Mitilor, Flexilor, Neucam, Zelorn, Lornistar-P
Synonyms :
lornoxicam
Class :
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Dosage Forms & StrengthsÂ
Tablet Â
4 mg Â
8 mgÂ
Take a dose of 8 to 16 mg orally daily
Daily dose not more than 24 mg
Take a dose of 12 mg daily in 2 to 3 divided doses
Daily dose not more than 16 mg
Not determined Â
Refer to adult dosingÂ
NSAIDs may increase the serum concentration of Lithium
NSAIDs may diminish the diuretic effect of loop diuretics
NSAIDs may diminish the diuretic effect of loop diuretics
NSAIDs may diminish the diuretic effect of loop diuretics
CYP2C9 enhancers may decrease the the bioavailability of lornoxicam 
Ketorolac may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents
When loracarbef is used together with lornoxicam, the risk or seriousness of nephrotoxicity is enhanced
When lornoxicam is used together with sertraline, the risk or seriousness of bleeding may be enhanced
When lornoxicam is used together with bufexamac, this leads to enhanced risk or seriousness of adverse outcomes
lornoxicam leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
lornoxicam: it may decrease the excretion rate of abacavir
When lornoxicam is used together with nifenazone, this leads to enhanced risk or seriousness of adverse events
it enhances the serum potassium levels
may enhance the serum concentration of CYP2C9 inhibitors
may increase the anticoagulation effect when combined
abatacept: it may increase the metabolism of lornoxicam
abrocitinib: it may decrease the metabolism of lornoxicam
acebutolol: it may decrease the metabolism of lornoxicam
Actions and SpectrumÂ
lornoxicam works by inhibiting the enzyme cyclooxygenase (COX), specifically the isoform COX-1 and COX-2. Â
By inhibiting COX, it reduces the production of prostaglandins, which in turn helps to alleviate pain, reduce inflammation, and lower fever.
Frequency not defined Â
DyspepsiaÂ
NauseaÂ
Abdominal pain Â
Diarrhea Â
Hematologic disorders Â
CNS effectsÂ
Vomiting Â
HeadacheÂ
Visual disturbanceÂ
Dizziness Â
Fluid retentionÂ
Photosensitivity Â
PalpitationÂ
InsomniaÂ
TinnitusÂ
Nephrotoxicity Â
Alveolitis Â
Colitis induction Â
StomatitisÂ
PancreatitisÂ
Toxic epidermal necrolysis Â
Hypertension Â
SomnolenceÂ
Black Box WarningÂ
None
Contraindication/Caution:Â
Contraindication:Â
Caution:Â
Pregnancy consideration:Â
Pregnancy category: N/AÂ
Lactation: Excretion into human milk is unknown Â
Pregnancy Categories:        Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology Â
COX-1 is involved in maintaining physiological functions like gastrointestinal protection and platelet aggregation, while COX-2 is associated with inflammation. Â
Preferential inhibition of COX-2 helps to reduce inflammation and pain while potentially minimizing some of the gastrointestinal side effects associated with COX-1 inhibition.Â
PharmacodynamicsÂ
By inhibiting the production of prostaglandins, lornoxicam influences physiological processes which involve prostaglandins sensitize pain receptors at the site of injury or inflammation, contributing to the perception of pain. Â
By reducing prostaglandin production, lornoxicam helps alleviate pain associated with various conditions.Â
PharmacokineticsÂ
Absorption  Â
lornoxicam is absorbed from the gastrointestinal tract. Â
DistributionÂ
lornoxicam is distributed throughout the body’s tissues. Â
MetabolismÂ
lornoxicam undergoes metabolism in the liver.Â
Elimination and excretionÂ
lornoxicam is eliminated from the body through the kidneys.Â
AdministrationÂ
lornoxicam is available in the form of oral tablets or capsules.Â
Patient information leafletÂ
Generic Name: lornoxicamÂ
Why do we use lornoxicam?Â
lornoxicam is a non-steroidal anti-inflammatory drug (NSAID) that is used to relieve pain and reduce inflammation. Â
lornoxicam is indicated to manage the pain and inflammation associated with osteoarthritis.Â
lornoxicam can be used to alleviate pain and reduce inflammation in patients with rheumatoid arthritis.Â
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