Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Daktacort, Daktodor, Cortimyc, Brentacort
Synonyms :
Miconazole nitrate/ hydrocortisone
Class :
Antifugal/ Topical corticosteroids
Dosage Forms & Strengths
Cream
2%/ 1%
Ointment
2%/ 1%
Apply ointment topically over the affected part twice or thrice daily for about one week
indications: it is indicated in treating infected eczema
Apply cream topically over the affected part twice daily for one week
indications: it is indicated in the treatment of candidal intertrigo
Dosage Forms & Strengths
Cream
2%/ 1%
Ointment
2%/ 1%
For children above 10 years:
Apply ointment topically over the affected part twice or thrice daily for about one week
indications: it is used in treating infected eczema
For children above 10 years:
Apply cream topically over the affected part twice daily for one week
indications: it is used to treat candidal intertrigo
the activity of oral anticoagulants may be increased
the activity of oral anticoagulants may be increased
the activity of oral anticoagulants may be increased
the activity of oral anticoagulants may be increased
the activity of oral anticoagulants may be increased
Actions and spectrum:
Miconazole nitrate kills fungus by breaking down their cell walls. It stops fungi from growing. Hydrocortisone reduces swelling and allergic reactions. Hydrocortisone works by blocking chemicals that cause inflammation.
Frequency not defined
Skin irritation
Urticaria
Pruritis
Erythema
Skin hypopigmentation
Burning sensation
Rashes
Contact dermatitis
Inflammation of the skin
Irritability
Adrenal suppression
Black Box Warning
Do not get this medicine in your eyes.
Contraindication/Caution:
Contraindication:
Hypersensitivity
Angioedema
Anaphylaxis
Plaque psoriasis
Rosacea
Precautions:
Children < 10 years
Lactation
Pregnancy
Occlusive dressings
Pregnancy consideration:
It is not recommended to use miconazole nitrate/ hydrocortisone in pregnancy as corticosteroids can cross the placenta
Lactation:
It is not recommended to use miconazole nitrate/ hydrocortisone in lactation.
Pregnancy category:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
<b>Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
It’s made of two key parts. Miconazole nitrate stops fungus and bacteria from growing. Hydrocortisone reduces swelling and redness.
Pharmacodynamics:
Miconazole blocks fungus growth. Meanwhile, hydrocortisone acts on chemicals that trigger inflammation. It can also narrow blood vessels.
Pharmacokinetics:
Absorption
Miconazole nitrate applied topically only allows under 1% absorption into the body. Around 3% gets absorbed by the skin.
Distribution
Miconazole and hydrocortisone primarily bind to proteins in bloodstream.
Metabolism
Liver metabolizes hydrocortisone.
Elimination and excretion
Miconazole is mainly excreted through feces. A minor portion of unchanged miconazole, alongside its metabolites, is eliminated renally. Hydrocortisone exits predominantly as glucuronide conjugates via urine. Hydrocortisone has an approximate systemic half-life of 100 minutes.
Administration:
Applying Miconazole nitrate/hydrocortisone is simple. Use it as cream or ointment. Put it directly on affected areas. Gently rub it into skin till fully absorbed. Be careful. Don’t let it touch eyes, inside mouth, open wounds. This could irritate those sensitive spots.
Patient information leaflet
Generic Name: miconazole nitrate/ hydrocortisone
Why do we use miconazole nitrate/ hydrocortisone?
Miconazole nitrate/hydrocortisone treats eczema, dermatitis, athlete’s foot, and thrush. It works well for inflammatory intertrigo and genital dermatitis. Miconazole nitrate fights fungal infections. Hydrocortisone reduces inflammation and itching. The medication relieves and heals various skin conditions.
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