Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
Brand Name :
nadofaragene firadenovec-vncg, Adstiladrin
Synonyms :
nadofaragene firadenovec
Class :
Biological Response Modifiers
Dosage Forms & Strengths
Intravesical solution
3 x 1011 viral particles (vp)/mL
Each vial contains 20 mL
Once every three months, instill 75 mL of 3 x 1011 viral particles (vp)/mL into the bladder.
Safety and efficacy not established
may have an increased adverse effect when combined with nadofaragene firadenovec
may have an increased adverse effect when combined with nadofaragene firadenovec
may have an increased adverse effect when combined with nadofaragene firadenovec
may have an increased adverse effect when combined with nadofaragene firadenovec
may have an increased adverse effect when combined with nadofaragene firadenovec
may have an increasingly adverse effect when combined with nadofaragene firadenovec
may have an increasingly adverse effect when combined with nadofaragene firadenovec
may have an increasingly adverse effect when combined with nadofaragene firadenovec
may have an increasingly adverse effect when combined with nadofaragene firadenovec
may have an increasingly adverse effect when combined with nadofaragene firadenovec
immunostimulants: they may increase the toxic effect of nadofaragene firadenovec
immunostimulants: they may increase the toxic effect of nadofaragene firadenovec
immunostimulants: they may increase the toxic effect of nadofaragene firadenovec
immunostimulants: they may increase the toxic effect of nadofaragene firadenovec
immunostimulants: they may increase the toxic effect of nadofaragene firadenovec
nadofaragene firadenovec: they may increase the immunosuppressive effect of selective immunosuppressants
nadofaragene firadenovec: they may increase the immunosuppressive effect of selective immunosuppressants
nadofaragene firadenovec: they may increase the immunosuppressive effect of selective immunosuppressants
may increase the toxic effect of immunosuppressants
may increase the adverse effect of Immunosuppressants
Adverse drug reactions
Frequency Defined
>10%
Hematuria (17%)
Creatinine increased (17%)
Bladder spasm (20%)
Instillation site discharge (33%)
Glucose increased, all grades (38%)
Micturition urgency (19%)
Triglycerides increased, all grades (30%)
Fatigue (24%)
Pyrexia (15%)
Hemoglobin decreased (16%)
Phosphate decreased, all grades (16%)
1-10%
Atrial fibrillation (1.3%)
Syncope (fainting) (1.3%)
Phosphate decreased (1.4%)
Glucose increased (6%)
Acute coronary syndrome (1.3%)
Triglycerides increased (1.9%)
Hypoglycemia
Coronary artery disease (1.3%)
<1%
Sepsis (0.6%)
Heart failure (0.6%)
Brain edema (swelling) (0.6%)
Bile duct stone (0.6%)
Pericarditis, (0.6%)
Pregnancy warnings:
Pregnancy:
US FDA pregnancy category: Not Assigned
Lactation:
Excreted into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient Information Leaflet
Generic Name: nadofaragene firadenovec
Why do we use nadofaragene firadenovec?
nadofaragene firadenovec is an Biological Response Modifiers and Gene Therapies, used to treat Bladder cancer.