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Brand Name :
Resealoid, Cinnasil, Moderil
Synonyms :
rescinnamine, reserpinine
Class :
Antihypertensive Agents
Brand Name :
Resealoid, Cinnasil, Moderil
Synonyms :
rescinnamine, reserpinine
Class :
Antihypertensive Agents
Safety and efficacy were not established
Refer to the adult dosing regimen
may increase the adverse effect of angiotensin ii receptor blockers
may increase the adverse effect of angiotensin ii receptor blockers
may increase the adverse effect of angiotensin ii receptor blockers
may increase the adverse effect of angiotensin ii receptor blockers
may increase the adverse effect of angiotensin ii receptor blockers
may have an increased hyperkalemic effect when combined with angiotensin-converting enzyme inhibitors
may have an increasingly adverse effect when combined with angiotensin-converting enzyme inhibitors
may have an increasingly adverse effect when combined with angiotensin-converting enzyme inhibitors
may have an increasingly adverse effect when combined with angiotensin-converting enzyme inhibitors
may have an increasingly adverse effect when combined with angiotensin-converting enzyme inhibitors
may have an increasingly adverse effect when combined with angiotensin-converting enzyme inhibitors
may have an increasingly adverse effect when combined with ACE inhibitors
may enhance the concentration of serum when combined with lithium
grass pollens allergen extract
may have an increasingly adverse effect when combined with grass pollen extract
choline magnesium trisalicylate
may enhance the nephrotoxic effect of ACE inhibitors
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may increase the risk of adverse/toxic effects
may increase the risk of adverse/toxic effects
may increase the risk of adverse/toxic effects
may increase the risk of adverse/toxic effects
may increase the risk of adverse/toxic effects
it may diminish the excretion rate when combined with vinca alkoloids, resulting in an enhanced serum level
may have an increased therapeutic effect when combined with angiotensin II receptor blocker
may have an increased therapeutic effect when combined with angiotensin II receptor blocker
may have an increased therapeutic effect when combined with angiotensin II receptor blocker
may have an increased therapeutic effect when combined with angiotensin II receptor blocker
may have an increased therapeutic effect when combined with angiotensin II receptor blocker
may have an increased hyperkalemic effect when combined with angiotensin-converting enzyme inhibitors
may have an increased hyperkalemic effect when combined with angiotensin-converting enzyme inhibitors
may have an increased hyperkalemic effect when combined with angiotensin-converting enzyme inhibitors
may have an increasingly adverse effect when combined with NSAIDs
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased therapeutic effect when combined with angiotensin II receptor blocker
may have an increased therapeutic effect when combined with angiotensin II receptor blocker
may have an increased myelosuppressive effect when combined with azathioprine
may have an increased hyperkalemic effect when combined with angiotensin-converting enzyme inhibitors
spironolactone and hydrochlorothiazide
may increase the hyperkalemic effect of ACE Inhibitors
may increase the hyperkalemic effect of ACE Inhibitors
may increase the hyperkalemic effect of ACE Inhibitors
may increase the hyperkalemic effect of ACE Inhibitors
may increase the hyperkalemic effect of ACE Inhibitors
may increase the hyperkalemic effect when combined with ace inhibitors
may increase the toxic effects of dipeptidyl peptidase-IV inhibitors
may have an increasingly adverse effect when combined with angiotensin-converting enzyme inhibitors
may have an increasingly adverse effect when combined with angiotensin-converting enzyme inhibitors
may have an increased hypotensive effect when combined with angiotensin-converting enzyme inhibitors
may have an increased hypotensive effect when combined with angiotensin-converting enzyme inhibitors
sodium ferric gluconate complex
concomitant administration of ACE inhibitors with sodium ferric gluconate complex should be used with caution as it may cause possible adverse reactions like hypersensitivity and low blood pressure
may have an increased hyperkalemic effect when combined with angiotensin-converting enzyme inhibitors
may have an increased hyperkalemic effect when combined with angiotensin-converting enzyme inhibitors
may have an increased hyperkalemic effect when combined with angiotensin-converting enzyme inhibitors
Actions and spectrum:
rescinnamine is a medication that belongs to a class of drugs called antihypertensives. It is primarily used to treat high blood pressure (hypertension). Its action involves dilating blood vessels and reducing the workload on the heart, which helps lower blood pressure.
The spectrum of action of rescinnamine is related to its antihypertensive effects. It is part of a group of drugs known as rauwolfia alkaloids and works by interfering with the function of certain receptors in the nervous system that regulate blood pressure.
Frequency not defined
Nasal congestion
CNS disorders
breast engorgement
gynecomastia
impotence
Oedema
weight gain
dry mouth
dysuria
Pruritus
headache
GI disturbances
galactorrhoea
decreased libido
Na retention
increased appetite
Miosis
sialorrhoea
rashes
thrombocytopaenic purpura
Black Box Warning:
There is no specific black box warning associated with rescinnamine.
Contraindication/Caution:
Contraindication:
Caution:
Comorbidities:
Pregnancy consideration: pregnancy category: not assigned
Lactation: excreted into human milk: unknown
Pregnancy category:
Pharmacology:
rescinnamine is an antihypertensive medication that belongs to the class of drugs known as rauwolfia alkaloids. It primarily acts by blocking the sympathetic nervous system’s stimulation of blood vessels and the heart, resulting in vasodilation (widening of blood vessels) and a decrease in heart rate.
This effect lowers blood pressure, making it effective in the treatment of hypertension. rescinnamine’s mechanism of action involves inhibiting the release of norepinephrine (a neurotransmitter) from nerve endings, which reduces the sympathetic tone on the cardiovascular system. This pharmacological action helps to relax and dilate blood vessels, reducing the heart’s workload and lowering blood pressure levels.
Pharmacodynamics:
Pharmacokinetics:
Absorption
rescinnamine is administered orally, typically in tablet form. It is absorbed from gastrointestinal tract into the bloodstream.
Distribution
rescinnamine is distributed throughout the body, including various tissues and organs.
Metabolism
It is metabolized into various metabolites through enzymatic processes. These metabolites can have pharmacological activity.
Elimination and excretion
After metabolism, rescinnamine and its metabolites are excreted primarily through the kidneys. Renal excretion is main route of elimination. rescinnamine and its metabolites are excreted in the urine.
Administration:
Patient information leaflet
Generic Name: rescinnamine
Pronounced: (ree-SIN-uh-meen)
Why do we use rescinnamine?
rescinnamine is used to lower and manage high blood pressure (hypertension). It relaxes blood vessels and reduces the force of the heart’s contractions, thereby helping decrease blood pressure. It belongs to a class of drugs known as antihypertensives and has been used for its blood pressure-lowering effects.
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