agrimony

Action and Spectrum

Actions and Spectrum: 

Mechanism of Action: 

• Antioxidant Activity: agrimony contains various phenolic compounds, such as tannins, flavonoids, and phenolic acids, which possess antioxidant properties. These antioxidants can help neutralize harmful free radicals and protect cells from oxidative damage. 
• Anti-inflammatory Effects: Some studies suggest that agrimony may have anti-inflammatory effects. It may inhibit the production of inflammatory mediators, such as cytokines and prostaglandins, involved in the inflammatory response. 
• Astringent Properties: agrimony is known for its astringent properties, which may be attributed to the presence of tannins. Astringents can help tighten and tone tissues, leading to a drying and tightening effect. This property may help manage conditions such as diarrhea and wound healing. 

Spectrum of Activity:  

The spectrum of activity of agrimony needs to be well-established, and its effects may vary depending on the specific application. Traditionally, agrimony has been used for various purposes, including: 

• Digestive Health: agrimony has been used to support digestive health, particularly for conditions like diarrhea, gastritis, and gastrointestinal discomfort. 
• Wound Healing: Topical applications of agrimony have been used to aid in wound healing and promote skin health. 
• Anti-inflammatory and Antispasmodic Effects: agrimony has been employed to alleviate symptoms associated with inflammation and spasms, such as sore throat, cough, and mouth ulcers. 

Drug Interaction

Adverse Reaction

None

Black Box Warning

Black box warning: 

None 

Contraindication / Caution

Contraindications/caution: 

Contraindications: 

Constipation 

Renal/hepatic impairment 

Caution: 

• Allergic Reactions: Some individuals may be allergic to agrimony or plants in the Rosaceae family, which includes agrimony. If you have known allergies to these plants, it is advisable to avoid agrimony. 
• Pregnancy and Breastfeeding: The safety of using agrimony during pregnancy and breastfeeding has not been established. It is recommended to avoid using agrimony during these periods unless directed by a healthcare professional. 
• Surgery: agrimony may have effects on blood clotting and blood sugar levels.

Pregnancy / Lactation

Pregnancy consideration: N/A 

Lactation: N/A 

Pregnancy category: 

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester. 

Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. 

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.    

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.    

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.    

Category N: There is no data available for the drug under this category 

Pharmacology

Pharmacology: 

• Antioxidant Activity: agrimony contains various phenolic compounds, including flavonoids, tannins, and phenolic acids, which possess antioxidant properties. These antioxidants can help neutralize harmful free radicals and protect cells from oxidative damage. 
• Anti-inflammatory Effects: Some studies suggest that agrimony may have anti-inflammatory effects. It may inhibit the production of inflammatory mediators, such as cytokines and prostaglandins, involved in the inflammatory response. 
• Astringent Properties: agrimony is well-known for its astringent properties, which are believed to be due to the presence of tannins. Astringents have a constricting and drying effect on tissues. agrimony’s astringent properties may help manage conditions such as diarrhea, sore throat, and mouth ulcers. 
• Diuretic Effects: agrimony has been traditionally used to increase urine production and promote the elimination of excess fluids from the body. 

Pharmacokinetics: 

N/A 

Adminstartion

Pharmacology: 

• Antioxidant Activity: agrimony contains various phenolic compounds, including flavonoids, tannins, and phenolic acids, which possess antioxidant properties. These antioxidants can help neutralize harmful free radicals and protect cells from oxidative damage. 
• Anti-inflammatory Effects: Some studies suggest that agrimony may have anti-inflammatory effects. It may inhibit the production of inflammatory mediators, such as cytokines and prostaglandins, involved in the inflammatory response. 
• Astringent Properties: agrimony is well-known for its astringent properties, which are believed to be due to the presence of tannins. Astringents have a constricting and drying effect on tissues. agrimony’s astringent properties may help manage conditions such as diarrhea, sore throat, and mouth ulcers. 
• Diuretic Effects: agrimony has been traditionally used to increase urine production and promote the elimination of excess fluids from the body. 

Pharmacokinetics: 

N/A 

Patient Information Leaflet

Patient information leaflet 

Generic Name: agrimony 

Why do we use agrimony? 

agrimony (agrimonia eupatoria) has a variety of traditional uses. Here are some common uses of agrimony in brief: 

• Digestive Health: agrimony supports digestive health, alleviating symptoms such as diarrhea, indigestion, and stomach discomfort. 
• Astringent Properties: agrimony has astringent properties and is used to help reduce excessive secretions or discharge, such as in cases of diarrhea, sore throat, and mouth ulcers. 
• Skin Conditions: agrimony is sometimes used topically for its potential benefits on skin health. It may be applied to soothe skin irritations, wounds, or minor skin conditions. 
• Respiratory Support: agrimony has been traditionally used for respiratory conditions such as coughs and sore throats, possibly due to its potential soothing and anti-inflammatory effects. 
• Urinary Health: agrimony has been used as a traditional diuretic to increase urine production and support urinary health, although scientific evidence supporting this use is limited.