RYBREVANT FASPRO™ Receives FDA Approval for First-Line EGFR-Mutated NSCLC
December 26, 2025
Brand Name :
Slynd
(United States) [Available]Synonyms :
Class :
Progestins; Spironolactone derivatives
Dosage forms & Strengths:
Adult:
Tablet:
4 mg
Safety and efficacy are not seen in females before menarche
After menarche, refer to adult dosing
may diminish the concentration of serum when combined with hormonal contraceptives
may diminish the concentration of serum when combined with hormonal contraceptives
may diminish the concentration of serum when combined with hormonal contraceptives
may diminish the concentration of serum when combined with hormonal contraceptives
may diminish the concentration of serum when combined with hormonal contraceptives
etonogestrel/ethinyl estradiol
may diminish the serum concentration of each other when combined
may diminish the concentration of serum when combined with hormonal contraceptives
may diminish the concentration of serum when combined with hormonal contraceptives
may diminish the concentration of serum when combined with hormonal contraceptives
may diminish the concentration of serum when combined with hormonal contraceptives
may diminish the concentration of serum when combined with hormonal contraceptives
asunaprevir: they may diminish the serum concentration of hormonal contraceptives
efavirenz: they may diminish the serum concentration of hormonal contraceptives
fosaprepitant: they may diminish the serum concentration of hormonal contraceptives
ixazomib: they may diminish the serum concentration of hormonal contraceptives
topiramate: they may diminish the serum concentration of hormonal contraceptives
anastrozole: they may diminish the serum concentration of hormonal contraceptives
may diminish the serum concentration when combined with hormonal contraceptives
may diminish the serum concentration when combined with hormonal contraceptives
It may enhance the effect when combined with lonafarnib by affecting CYP3A4 metabolism
ulipristal: they may decrease the therapeutic effect of progestins
Could potentially reduce the concentration serum of hormonal contraceptives
Could potentially reduce the concentration serum of hormonal contraceptives
Could potentially reduce the concentration serum of hormonal contraceptives
Hormonal Contraceptives increase the effect of thrombogenesis of tranexamic acid
the serum levels of potassium may be increased
may enhance the serum concentration when combined with hormonal contraceptives
may enhance the serum concentration when combined with hormonal contraceptives
may enhance the serum concentration when combined with hormonal contraceptives
may enhance the serum concentration when combined with hormonal contraceptives
may enhance the serum concentration when combined with hormonal contraceptives
it may diminish the excretion rate when combined with corifollitropin alfa resulting in an enhanced serum level
retinoic acid derivatives decrease the efficacy of progestins
retinoic acid derivatives decrease the efficacy of progestins
retinoic acid derivatives decrease the efficacy of progestins
retinoic acid derivatives decrease the efficacy of progestins
retinoic acid derivatives decrease the efficacy of progestins
When indisulam is used together with drospirenone, this leads to a reduction in drospirenone metabolism
When drospirenone is used together with clomocycline, this leads to reduction in concentration serum of clomocycline
drospirenone: it may increase the therapeutic efficacy of with pheneticillin
progestins could potentially intensify the Harmful/toxic effects of chlorprothixene
could potentially lead to a reduction in the concentration serum of Hormonal Contraceptives
The concentration serum of flibanserin may be intensified by hormonal contraceptive
it may reduce the therapeutic effect of the drug
The thrombogenic effect of carfilzomib might be intensified using hormonal contraceptives
Could potentially lead to a reduction in the concentration serum of hormonal contraceptives
>10%:
Unscheduled bleeding
1-10%:
Acne
Metrorrhagia
Breast pain
Vaginal hemorrhage
Weight increased
Dysmenorrhea
Nausea
Headache
Menstruation irregular
Libido decreased
Breast tenderness
Drospirenone is contraindicated in patients hypersensitive to it or other components in the formulation.
It is also contraindicated in patients with renal impairment, cervical cancer, and adrenal insufficiency.
Pregnancy consideration:
Drospirenone therapy is not indicated for pregnant women.
Breastfeeding warnings:
Drospirenone doesn’t affect breastfed infants.
Pregnancy category:
Patient information leaflet
Generic Name: Drospirenone
Pronounced: dros-pire-none
Why do we use drospirenone?
Drospirenone helps in contraception.