Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Loxomac
Synonyms :
loxoprofen
Class :
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Dosage Forms & StrengthsÂ
Tablet Â
60 mg
Take a dose of 60 mg orally three times a day or 120 mg as a single daily dose
Not determined Â
Refer to adult dosingÂ
NSAIDS may enhance the neuroexcitatory and/or seizure-potentiating effect of quinolones
NSAIDS may enhance the neuroexcitatory and/or seizure-potentiating effect of quinolones
Corticosteroids may enhance the adverse/toxic effect of nonsteroidal Anti-Inflammatory agents
Corticosteroids may enhance the adverse/toxic effect of nonsteroidal Anti-Inflammatory agents
Corticosteroids may enhance the adverse/toxic effect of nonsteroidal Anti-Inflammatory agents
Corticosteroids may enhance the adverse/toxic effect of nonsteroidal Anti-Inflammatory agents
Corticosteroids may enhance the adverse/toxic effect of nonsteroidal Anti-Inflammatory agents
When loxoprofen is used together with sertraline, the risk or seriousness of bleeding may be enhanced
When loxoprofen is used together with bufexamac, this leads to enhanced risk or seriousness of adverse outcomes
loxoprofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
When loxoprofen is used together with nifenazone, this leads to enhanced risk or seriousness of adverse events
When loxoprofen is used together with diazoxide, this leads to reduction in therapeutic effectiveness of diazoxide
angiotensin-Converting Enzyme Inhibitors may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents
angiotensin-Converting Enzyme Inhibitors may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents
angiotensin-Converting Enzyme Inhibitors may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents
angiotensin-Converting Enzyme Inhibitors may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents
angiotensin-Converting Enzyme Inhibitors may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents
may increase the risk or severity of hypertension when combined
Actions and SpectrumÂ
The cyclooxygenase inhibitor loxoprofen is non-selective. Prostaglandins are made from arachidonic acid hence it reduces that process. It is a prodrug that, when administered orally, quickly changes into its active metabolite. Â
Frequency not defined Â
AnemiaÂ
Leucopenia Â
Diarrhea Â
Constipation Â
AnorexiaÂ
Vomiting Â
ThrombocytopeniaÂ
Black Box WarningÂ
None
Contraindication/Caution:Â
Contraindication:Â
Caution:Â
Pregnancy consideration:Â
Pregnancy category: N/AÂ
Lactation: Excretion into human milk is unknown Â
Pregnancy Categories:        Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology Â
loxoprofen is an NSAID commonly used to alleviate pain and inflammation. The mechanism of action involves inhibiting COX enzymes, which reduces the production of prostaglandins. Â
PharmacodynamicsÂ
The inhibition of prostaglandin synthesis results in a reduction in pain. loxoprofen’s analgesic effects make it effective for managing various types of pain, ranging from musculoskeletal pain to dental pain.Â
PharmacokineticsÂ
Absorption  Â
loxoprofen is rapidly absorbed from the gastrointestinal tract after.Â
DistributionÂ
loxoprofen has a moderate degree of plasma protein binding.Â
MetabolismÂ
loxoprofen undergoes metabolism primarily in the liver through oxidation.Â
Elimination and excretionÂ
loxoprofen and its metabolites are primarily excreted in the urine. Â
AdministrationÂ
loxoprofen is administered orally in the form of tablets.
Patient information leafletÂ
Generic Name: loxoprofenÂ
Why do we use loxoprofen?Â
loxoprofen is used to manage pain and inflammation caused by acute injuries, such as sprains and strains. Â
loxoprofen can be prescribed to manage postoperative pain and inflammation.  Â
loxoprofen is indicated to relieve pain and inflammation associated with musculoskeletal disorders.Â
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
