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November 16, 2025
Brand Name :
Camzyos
Synonyms :
mavacamten
Class :
Cardiac Myosin Inhibitors
Dosage forms & Strengths:Â
Adult:Â
CapsuleÂ
2.5 mgÂ
5 mgÂ
10 mgÂ
15 mgÂ
5
mg
Capsule
Orally 
every day
Safety and efficacy are not seen in pediatricsÂ
Safety and efficacy are not seen in pediatrics
It may enhance the effect when combined with grapefruit by CYP3A4 metabolism
mavacamten: they may diminish the serum concentration of hormonal contraceptives
mavacamten: they may diminish the serum concentration of hormonal contraceptives
mavacamten: they may diminish the serum concentration of hormonal contraceptives
mavacamten: they may diminish the serum concentration of hormonal contraceptives
It may enhance the effect when combined with cannabidiol by affecting CYP2C19 metabolism
CYP3A4 Inhibitors: they may enhance the serum concentration of mavacamten
CYP3A4 Inhibitors: they may enhance the serum concentration of mavacamten
CYP3A4 Inhibitors: they may enhance the serum concentration of mavacamten
CYP3A4 Inhibitors: they may enhance the serum concentration of mavacamten
CYP3A4 Inhibitors: they may enhance the serum concentration of mavacamten
may diminish the serum concentration of Hormonal Contraceptives
mavacamten decreases the activity of norethisterone
by altering intestinal/hepatic CYP 3A4 metabolism, the activity of mavacamten can be reduced by butabarbital
mavacamten: they may diminish the serum concentration of CYP3A4 Inducers
mavacamten: they may diminish the serum concentration of CYP3A4 Inducers
mavacamten: they may diminish the serum concentration of CYP3A4 Inducers
mavacamten: they may diminish the serum concentration of CYP3A4 Inducers
mavacamten: they may diminish the serum concentration of CYP3A4 Inducers
may enhance the concentration of serum when combined with mavacamten
may enhance the concentration of serum when combined with mavacamten
mavacamten: they may enhance the serum concentration of CYP2D6 Inhibitors
mavacamten: they may enhance the serum concentration of CYP2D6 Inhibitors
mavacamten: they may enhance the serum concentration of CYP2D6 Inhibitors
mavacamten: they may enhance the serum concentration of CYP2D6 Inhibitors
mavacamten: they may enhance the serum concentration of CYP2D6 Inhibitors
may diminish the serum concentration of CYP3A4 Inducers
mavacamten: they may increase the toxic effect of Beta-Blockers
may diminish the serum concentration of CYP3A4 Substrates
>10%:Â
DizzinessÂ
1-10%:Â
SyncopeÂ
Reduced LVEFÂ
Mavacamten is contraindicated in patients hypersensitive to the active ingredient.Â
Pregnancy consideration:Â Â
The drug may cause harm to the fetus if administered in pregnant females.Â
Breastfeeding warnings:Â Â
No data is available regarding the excretion of the drug in breast milk.Â
Pregnancy category:Â
Patient information leafletÂ
Generic Name: mavacamtenÂ
Pronounced: mav-a-kam-tenÂ
Why do we use mavacamten?Â
Mavacamten is a cardiac myosin inhibitor. It is used to treat Obstructive Hypertrophic Cardiomyopathy.  Â