- March 15, 2022
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Brand Name :
Viramune, Viramune XR
Synonyms :
nevirapine
Class :
Antiviral agents and Anti-HIV (antiretroviral)
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Brand Name :
Viramune, Viramune XR
Synonyms :
nevirapine
Class :
Antiviral agents and Anti-HIV (antiretroviral)
Dosage Forms & Strengths
Suspension, Oral:
50 mg/5 ml
Tablet, Oral:
200 mg
Tablet extended release:
100 mg
400 mg
Note: Nevirapine is not recommended as an initial line of therapy for the treatment of HIV in adults.
Avoid in case of hepatotoxicity.
Use preferred in combination with other antiretroviral agents.
Dosage Forms & Strengths
Suspension, Oral:
50 mg/5 ml
Tablet, Oral:
200 mg
Tablet extended release:
100 mg
400 mg
Note: Nevirapine is not recommended as an initial line of therapy for the treatment of HIV in adults.
Avoid in case of hepatotoxicity.
Use preferred in combination with other antiretroviral agents.
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
when both drugs are combined, there may be a reduced effect of abemaciclib by affecting hepatic or intestinal enzyme cyp3a4 metabolism
the effect of nevirapine is decreased by lorlatinib, by altering intestinal or hepatic CYP3A4 enzyme metabolism
nevirapine decreases the effect of ixazomib by altering intestinal/hepatic CYP3A4 enzyme metabolism
CYP3A strong enhancers of the small intestine may reduce the bioavailability of nevirapine
it decreases the effect or level of palbociclib by altering the intestinal or hepatic CYP3A4 enzyme metabolism
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
reverse transcriptase inhibitors increase the concentration of ergonovine in the serum
may enhance the serum concentration of simeprevir
when both drugs are combined, there may be a decreased metabolism of paclitaxel
when both drugs are combined, there may be an increased effect of cabozantinib
increases serum level of cabazitaxel by affecting the enzyme CYP3A4
Frequency defined:
>10%
Skin rash
Increased serum cholesterol
1% to 10%:
Angina pectoris
Facial edema
Atrial fibrillation
Myocardial infarction
Syncope
Peripheral neuropathy
Abnormal dreams
Anxiety
Confusion
Drowsiness
Disorientation
Disturbance in attention
Nervousness
Hypoesthesia
Prurigo
Night sweats
Xeroderma
Diabetes
lipohypertrophy
pancreatitis
stomatitis
anorexia
constipation
flatulence
gastritis
Post-marketing:
Angioedema
Erythema multiforme
Hemorrhagic stroke
Rhabdomyolysis
Stevens-Johnson syndrome
Dress syndrome
Pregnancy consideration: Nevirapine can transfer in high amounts across the human placenta.
Lactation: Nevirapine can be present in breast milk.
Pregnancy category:
Patient information leaflet
Generic Name: Nevirapine
Pronunciation: nevirapine
Why do we use Nevirapine?
It is used to treat viral infections such as HIV-1 infection.
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