Performance Comparison of Microfluidic and Immunomagnetic Platforms for Pancreatic CTC Enrichment
November 15, 2025
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Brand Name :
No Data Available.
Synonyms :
oxtriphylline
Class :
Methylxanthines
Brand Name :
No Data Available.
Synonyms :
oxtriphylline
Class :
Methylxanthines
Dosage Forms & StrengthsÂ
Tablet Â
200 mg Â
400 mg Â
600 mg Â
Take a maintenance dose orally of 4.7 mg/kg in each 8 hours
Dosage Forms & StrengthsÂ
Tablet Â
200 mg Â
400 mg Â
600 mg Â
for 1 to 9 years old:
Take a maintenance dose orally of 6.2 mg/kg in each 6 hours
for 9 to 16 years old:
Take a maintenance dose orally of 4.7 mg/kg in each 6 hours
Refer to adult dosingÂ
amobarbital: it may decreased the serum concentration of oxtriphylline
amphetamine: it may increase the risk of adverse effects of oxtriphylline
anagrelide: it may decrease the metabolism of oxtriphylline
anakinra: it may increase the metabolism of oxtriphylline
antipyrine: it may decrease the metabolism of oxtriphylline
arformoterol: it may increase the risk of hypokalemia with oxtriphylline
binimetinib: it may decrease the metabolism of oxtriphylline
bisoprolol: it may increase the risk of adverse effects of oxtriphylline
bortezomib: it may decrease the metabolism of oxtriphylline
brexanolone: it may increase the excretion rate of oxtriphylline
brivaracetam: it may increase the excretion rate of oxtriphylline
bromazepam: it may decrease the therapeutic efficacy of oxtriphylline
carvedilol: it may increase the risk of adverse effects of oxtriphylline
celiprolol: it may increase the risk of adverse effects of oxtriphylline
Cenobamate: it may increase the excretion rate of oxtriphylline
chlordiazepoxide: it may decrease the therapeutic efficacy of oxtriphylline
chlorpromazine: it may decrease the metabolism of oxtriphylline
Actions and SpectrumÂ
oxtriphylline works primarily by inhibiting the enzyme phosphodiesterase (PDE). This leads to an increase in cyclic adenosine monophosphate (cAMP) levels within cells. The elevated cAMP levels result in relaxation of smooth muscles in the airways, leading to bronchodilation.  Â
Frequency not defined Â
SeizuresÂ
Irregular heartbeat Â
Difficulty in breathingÂ
Nausea or vomitingÂ
Throat irritationÂ
Swelling of lips, tongue, face, or hivesÂ
Black Box WarningÂ
NoneÂ
Contraindication/Caution:Â
Contraindication:Â
Caution:Â
Pregnancy consideration:Â
Pregnancy category: N/AÂ
Lactation: Excretion into human milk is unknown Â
Pregnancy Categories:        Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology Â
oxtriphylline’s pharmacological effect is the relaxation of smooth muscles in the bronchial airways. Â
This leads to widening of the airways, improved airflow, and relief from symptoms such as wheezing and shortness of breath.Â
PharmacodynamicsÂ
The relaxation of smooth muscles in the bronchial airways leads to bronchodilation. Â
This effect is effective in relieving the symptoms of airway constriction seen in conditions like asthma and COPD.Â
PharmacokineticsÂ
Absorption  Â
oxtriphylline is absorbed in the gastrointestinal tract. Â
DistributionÂ
oxtriphylline is distributed throughout the body via the bloodstream. Â
MetabolismÂ
oxtriphylline undergoes metabolism in the liver through enzymatic processes by cytochrome P450 enzymes. Â
Elimination and excretionÂ
oxtriphylline and its metabolites are excreted through the kidneys.
AdministrationÂ
oxtriphylline is administered orally in the form of tablets and capsules.
Patient information leafletÂ
Generic Name: oxtriphyllineÂ
Why do we use oxtriphylline?Â
oxtriphylline is used in treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD).  Â
oxtriphylline is a bronchodilator used for the treatment of emphysema.Â
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