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Brand Name :
N/A
Synonyms :
Potassium nitrate
Class :
Inorganic nitrate salts
Dosage Forms & Strengths
Toothpaste
50g
Tooth Sensitivity
To be taken as directed by the physician
Toothache
To be taken as directed by the physician
to be used as advised by the doctor
to be used as advised by the doctor
Data not available
Refer to adult dosing
the rate of excretion of potassium nitrate may be reduced
the hyperkalemic activity of acebutolol may be increased
the hyperkalemic activity of aceclofenac may be increased
the hyperkalemic activity of acemetacin may be increased
the hyperkalemic activity of acetylsalicylic acid may be increased
the rate of excretion of potassium nitrate may be reduced
the activity of potassium nitrate may be reduced due to an increase in the rate of excretion
the hyperkalemic activity of betaxolol may be increased
the rate of excretion of potassium nitrate may be reduced
the risk of hyperkalemic activity may be increased
the hyperkalemic activity of carvedilol may be increased
the rate of excretion of potassium nitrate may be reduced
the hyperkalemic activity of valsartan may be increased
Actions and spectrum:
By diffusing through the dentinal tubules, potassium nitrate depolarizes the nerve cells. Consequently, these cells lose their ability to respond to excitatory indications.
Frequency not defined
Headache
Methemoglobinemia
Dizziness
Rash
Trouble breathing
Black Box Warning
Use with caution. Methemoglobinemia is reported
Contraindication/Caution:
Contraindication:
Hypersensitivity
Pregnancy consideration:
Limited data available
Lactation:
Limited data available
Pregnancy category:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
Pharmacodynamics:
Pharmacokinetics:
Absorption
Potassium nitrate is readily absorbed in the small intestine
Distribution
Nitrates are readily distributed into the systemic circulation
Metabolism
Nitrates are converted to nitrites in saliva and g.i. system through the bacteria
Elimination and excretion
Mainly as inorganic nitrites, nitrate is eliminated through urine
Half-life:
Administration:
Patient information leaflet
Generic Name: potassium nitrate
Why do we use potassium nitrate?
Potassium nitrate is used to relieve toothache and tooth sensitivity.