Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Tasmar
(United States) [Available]Synonyms :
Class :
Anti-Parkinson Agent and COMT Inhibitor
Brand Name :
Tasmar
(United States) [Available]Synonyms :
Class :
Anti-Parkinson Agent and COMT Inhibitor
Dosage Forms & Strengths
Tablet
100mg
100 mg orally 3 times a day as an adjunct to levodopa/carbidopa; and increased to 200 mg as tolerated orally 3 times a day
The Maximum dose per day is 600 mg
may have an increasingly adverse effect when combined with MAO inhibitors
may have an increasingly adverse effect when combined with MAO inhibitors
may have an increasingly adverse effect when combined with MAO inhibitors
may have an increasingly adverse effect when combined with MAO inhibitors
may have an increasingly adverse effect when combined with MAO inhibitors
may have an increasingly adverse effect when combined with MAO inhibitors
may enhance the adverse/toxic effect of MOA inhibitors
may enhance the adverse/toxic effect of MOA inhibitors
may enhance the adverse/toxic effect of MOA inhibitors
may enhance the adverse/toxic effect of MOA inhibitors
may enhance the adverse/toxic effect of MOA inhibitors
It may enhance the serum concentration when combined with COMT Substrates
It may enhance the serum concentration when combined with COMT Substrates
It may enhance the serum concentration when combined with COMT Substrates
It may enhance the serum concentration when combined with COMT Substrates
when butobarbital and tolcapone are combined, there may be an increased chance or severity of CNS depression
tolcapone may lower the excretion rate of ioxilan, potentially resulting in a higher serum level
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may enhance the serum concentration of COMT Substrates
It may enhance the serum concentration when combined with COMT Substrates
It may enhance the serum concentration when combined with COMT Substrates
It may enhance the serum concentration when combined with COMT Substrates
It may enhance the serum concentration when combined with COMT Substrates
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
may diminish the therapeutic effect of the drug
Adverse drug reactions:
Frequency Defined
>10%
Muscle cramping
Somnolence
Dyskinesia
Nausea
Insomnia
Hallucinations
Excessive dreaming
Diarrhea
Anorexia
Dystonia
Orthostatic hypotension
Confusion
Headache
1-10%
Upper respiratory tract infections
Vomiting
Pregnancy warnings:
US FDA pregnancy category: C
Breastfeeding warnings:
The release of the drug into the human breastmilk is unknown
Pregnancy Categories:
Patient Information Leaflet
Generic Name: tolcapone
Pronounciation: TOLE-ka-pone
Why do we use tolcapone?
tolcapone belongs to the class Anti-Parkinson Agent and COMT Inhibitor used to treat Parkinson’s disease. It increases the levels of levodopa in the body.
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