Genomic Study Maps Shared Risk Factors for 14 Psychiatric Disorders
December 14, 2025
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Brand Name :
N/A
Synonyms :
Tyrotricina, tyrothricinium, tirotricina
Class :
Antibacterial, polypeptide, Mouth/throat preparations
Brand Name :
N/A
Synonyms :
Tyrotricina, tyrothricinium, tirotricina
Class :
Antibacterial, polypeptide, Mouth/throat preparations
Dosage Forms & Strengths
Lozenges
0.5mg
1mg
4mg
Throat spray
4mg
Topical gel
5mg/5g
One lozenge orally
Note: do not chew or swallow the whole tablet
(or)
Throat spray
Initial dose: spray orally 1-2times in about 2-3hours
Maintenance dose: spray orally once every six hours
One lozenge orally
Note: do not chew or swallow the whole tablet
(or)
Throat spray
Initial dose: spray orally 1-2times in about 2-3hours
Maintenance dose: spray orally once every six hours
One lozenge orally
Note: do not chew or swallow the whole tablet
(or)
Throat spray
Initial dose: spray orally 1-2times in about 2-3hours
Maintenance dose: spray orally once every six hours
Indication: indicated for use in the treatment of swallowing difficulty due to infections like pharyngitis, gingivitis, tonsilitis, and sore throat
One lozenge orally
Note: do not chew or swallow the whole tablet
(or)
Throat spray
Initial dose: spray orally 1-2times in about 2-3hours
Maintenance dose: spray orally once every six hours
Indication: indicated for use in the treatment of swallowing difficulty due to infections like pharyngitis, gingivitis, tonsilitis, and sore throat
One lozenge orally
Note: do not chew or swallow the whole tablet
(or)
Throat spray
Initial dose: spray orally 1-2times in about 2-3hours
Maintenance dose: spray orally once every six hours
Indication: indicated for use in the treatment of swallowing difficulty due to infections like pharyngitis, gingivitis, tonsilitis, and sore throat
A thin layer of drug to be applied on the affected area 2-3 times daily-
A thin layer of the drug to be applied on the affected area 2-3 times daily
Dosage Forms & Strengths
Lozenges
0.5mg
1mg
4mg
Throat spray
4mg
Topical gel
5mg/5g
For children aged 12 years and above:
One lozenge orally
Note: do not chew or swallow the whole tablet
(Or)
Throat spray
For children aged seven years and above:
Initial dose: spray orally 1-2times in about 2-3hours
Maintenance dose: spray orally once every six hours
For children aged 12 years and above:
One lozenge orally
Note: do not chew or swallow the whole tablet
(Or)
Throat spray
For children aged seven years and above:
Initial dose: spray orally 1-2times in about 2-3hours
Maintenance dose: spray orally once every six hours
One lozenge orally
Note: do not chew or swallow the whole tablet
(Or)
Throat spray
For children aged seven years and above:
Initial dose: spray orally 1-2times in about 2-3hours
Maintenance dose: spray orally once every six hours
One lozenge orally
Note: do not chew or swallow the whole tablet
(Or)
Throat spray
For children aged seven years and above:
Initial dose: spray orally 1-2times in about 2-3hours
Maintenance dose: spray orally once every six hours
Refer to adult dosing
the bradycardic activity of acebutolol may be increased
the risk of bleeding may be increased
the risk of adverse effects may be increased
the risk of methemoglobinemia may be increased
an increase in neuromuscular blocking activity of aclidinium may be increased
the therapeutic activity of amoxapine may be reduced
the risk of methemoglobinemia may be increased
the bradycardic activity of carvedilol may be increased
the risk of methemoglobinemia may be increased
the neuromuscular blocking activity of clevidipine may be increased
the risk of methemoglobinemia may be increased
the therapeutic activity of darifenacin may be reduced
the therapeutic activity of desloratadine may be reduced
the risk of bleeding may be increased
vibrio cholerae cvd 103-hgr strain live antigen
the therapeutic activity of vibrio cholerae CVD 103- Hg R strain live antigen may be reduced
the risk of bleeding can be increased
Actions and spectrum:
Tyrothricin acts by breaking down the bacterial cell walls, leading to the leakage of cell contents and hence inhibiting bacterial synthesis
Frequency not defined
Hepatic failure
Renal failure
Loss of smell for longer duration
Fatal: Stevens-Johnson syndrome
Black Box Warning
Not listed
Contraindication/Caution:
Contraindication:
Hypersensitivity
Congenital methemoglobinemia
Allergic to local anesthetics containing ester group
Pregnancy consideration:
USFDA pregnancy category: Not assigned
Lactation:
Data about the excretion of tyrothricin into breast milk is not known
Pregnancy category:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus `in either the first or second trimester.
Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
Tyrothricin is used to treat bacterial infections
Pharmacodynamics:
To facilitate the healing of wounds and other skin damage, this removes harmful bacteria from the affected area
Pharmacokinetics:
Absorption
Due to the lack of water-soluble properties, absorption through the skin is prevented
Distribution
Limited data available
Metabolism
Limited data available
Elimination and excretion
Limited data available
Half-life:
Limited data available
Administration:
Depending on the disease condition, administer tyrothricin as prescribed by the doctor
Patient information leaflet
Generic Name: tyrothricin
Why do we use tyrothricin?
Tyrothricin is used in the treatment of various oropharyngeal infections, sore throat, tonsilitis, pharyngitis, gingivitis, stomatitis, infections of minor wounds, etc. It is also effective against gram +ve bacilli and gram -ve cocci bacteria.
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