Microplastics and Misinformation: What Science Really Says
November 12, 2025
Brand Name :
CNJ-016
(United States) [Available]Synonyms :
Class :
Vaccines, Immune Globulins
Dosage Forms & Strengths Â
injectable solution Â
50mg/ml Â
Vaccinia Infection: Â
6,000 units/kg IV recommended; additional dose of 9,000 units/kg may be given if the patient does not respond to initial dose.  Â
24,000 unit/kg IV was tolerated as a single dose in healthy volunteers.Â
Renal Impairment Â
No dosage adjustment is required, use caution. Â
administer at a minimum rate of infusion Â
if renal deterioration worsens, discontinue the dose Â
6000
unit/kg
Intravenous (IV)
; additional dose of 9,000 units/kg may be given if the patient does not respond to initial dose.
24,000 unit/kg IV was tolerated as a single dose in healthy volunteers.
Dose Adjustments
Renal Impairment:
No dosage adjustment is required, use caution.
administer at a minimum rate of infusion
if renal deterioration worsens, discontinue the dose
immunosuppressants may diminish the therapeutic effect of vaccines
immunosuppressants may diminish the therapeutic effect of vaccines
immunosuppressants may diminish the therapeutic effect of vaccines
immunosuppressants may diminish the therapeutic effect of vaccines
immunosuppressants may diminish the therapeutic effect of vaccines
immunosuppressants may diminish the therapeutic effect of vaccines
immunosuppressants may diminish the therapeutic effect of vaccines
immunosuppressants may diminish the therapeutic effect of vaccines
Corticosteroids may diminish the therapeutic effect of Vaccines
Corticosteroids may diminish the therapeutic effect of Vaccines
Corticosteroids may diminish the therapeutic effect of Vaccines
Corticosteroids may diminish the therapeutic effect of Vaccines
Corticosteroids may diminish the therapeutic effect of Vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may enhance the adverse/toxic effect of varicella virus-containing vaccines
may enhance the adverse/toxic effect of varicella virus-containing vaccines
may enhance the risk of adverse/toxic effect of rubella- or varicella-containing live vaccines
may enhance the risk of adverse/toxic effect of rubella- or varicella-containing live vaccines
may enhance the risk of adverse/toxic effect of rubella- or varicella-containing live vaccines
may enhance the risk of adverse/toxic effect of rubella- or varicella-containing live vaccines
may enhance the risk of adverse/toxic effect of rubella- or varicella-containing live vaccines
may decrease the therapeutic effect of corticosteroids
may decrease the therapeutic effect of immunosuppressants
may decrease the therapeutic effect of immunosuppressants
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may increase the toxic effect of immunosuppressants
may increase the adverse effect of corticosteroids
may decrease the therapeutic effect of immunosuppressants
may decrease the therapeutic effect of immunosuppressants
may increase the adverse/toxic effect of immunosuppressants
may increase the adverse/toxic effect of immunosuppressants
may increase the adverse/toxic effect of immunosuppressants
may increase the adverse/toxic effect of immunosuppressants
may increase the adverse/toxic effect of immunosuppressants
Immunosuppressants may enhance the adverse/toxic effect of Vaccines
Immunosuppressants may enhance the adverse/toxic effect of Vaccines
Immunosuppressants may enhance the adverse/toxic effect of Vaccines
Immunosuppressants may enhance the adverse/toxic effect of Vaccines
Immunosuppressants may enhance the adverse/toxic effect of Vaccines
may enhance the adverse/toxic effect of rubella, and varicella vaccine, live 
may diminish the therapeutic effect of other vaccines
vaccinia immune globulin intravenous (Rx)
may diminish the therapeutic effect of other vaccines
may diminish the therapeutic effect of other vaccines
may diminish the therapeutic effect of other vaccines
may diminish the therapeutic effect of other vaccines
may diminish the therapeutic effect of other vaccines
vaccinia immune globulin intravenous (Rx)
may diminish the therapeutic effect of other vaccines
may diminish the therapeutic effect of other vaccines
may diminish the therapeutic effect of other vaccines
may diminish the therapeutic effect of other vaccines
poliovirus vaccine, live, trivalent
may diminish the therapeutic effect of other vaccines
poliovirus vaccine inactivated
may diminish the therapeutic effect of other vaccines
may diminish the therapeutic effect of other vaccines
smallpox (vaccinia) vaccine, live
may diminish the therapeutic effect of other vaccines
may diminish the therapeutic effect of other vaccines
may diminish the therapeutic effect of other vaccines
may diminish the therapeutic effect of other vaccines
may enhance the adverse/toxic effect of vaccines
Adverse drug reactions:  Â
Frequency defined:  Â
1-10%Â
DizzinessÂ
Abdominal painÂ
ArthralgiaÂ
ErythemaÂ
FlushingÂ
Skin lacerationsÂ
UrticariaÂ
HeadacheÂ
Injection site reactionsÂ
NauseaÂ
DyspneaÂ
URIÂ
Contact dermatitisÂ
 Â
Pregnancy warnings:    Â
US FDA pregnancy category: CÂ
Breastfeeding warnings: Â
The release of the drug into the human breastmilk is unknownÂ
Pregnancy Categories:     Â
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.     Â
Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women     Â
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women     Â
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits     Â
Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.     Â
Category N: There is no data available for the drug under this category
Patient Information Leaflet Â
Generic Name: vaccinia immune globulin intravenous (Rx) Â
Why do we use vaccinia immune globulin intravenous?Â
Vaccinia immune globulin intravenous (Rx) is used for active immunization to prevent smallpox disease complications and monkeypox