Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Depacon
Synonyms :
valproate sodium injection
Class :
Anticonvulsants; Antiepileptic agents
Brand Name :
Depacon
Synonyms :
valproate sodium injection
Class :
Anticonvulsants; Antiepileptic agents
Dosage forms & Strengths
IV solution (as valproate sodium)
100mg/mL
Indicated for Complex Partial Seizures
10-15 mg/kg IV divided 2 times a day infused over 1 hour
May be increased to 60 mg/kg daily
Maximum duration is 14 days (AS soon as possible switch to Oral)
Dosage forms & Strengths
IV solution (as valproate sodium)
100mg/mL
Indicated for Complex Partial Seizures
10-15 mg/kg IV divided 2 times a day infused over 1 hour
May be increased to 60 mg/kg daily
Maximum duration is 14 days (AS soon as possible switch to Oral)
Refer adult dosing
valproate products increase the concentration of lesinurad in serum
may have an increased hepatotoxic effect when combined with valproate products
valproate increases the concentration of serum barbiturates in the serum
valproate increases the concentration of serum barbiturates in the serum
valproate increases the concentration of serum barbiturates in the serum
valproate increases the concentration of serum barbiturates in the serum
valproate increases the concentration of serum barbiturates in the serum
valproate increases the hepatotoxicity of cannabidiol
it increases the effect of CNS depressants
valproate decreases the efficacy of apixaban
valproate increases the toxicity of bupivacaine
may enhance the serum concentration
it increases the concentration of valproate products in the serum
valproate products increase the CNS depressing effect of clobazam
valproate products decrease the efficacy of dabigatran etexilate
it decreases the concentration of valproate products in the serum
valproate products increase the concentration of rufinamide in serum
Frequency defined
10%
AlopeciaÂ
ThrombocytopeniaÂ
InfectionÂ
DizzinessÂ
NauseaÂ
DyspepsiaÂ
PainÂ
TremorÂ
AstheniaÂ
Flu-like symptomsÂ
1-10%:Â
Cardiac arrhythmiaÂ
EdemaÂ
HypotensionÂ
TachycardiaÂ
AmenorrheaÂ
Weight lossÂ
Fecal incontinenceÂ
Fungal infectionÂ
<1%:Â
InflammationÂ
EuphoriaÂ
HypoesthesiaÂ
VasodilationÂ
PharyngitisÂ
Valproate is contraindicated in patients hypersensitive to the formulation’s active ingredient and other excipients.Â
Pregnancy consideration:Â Â
Valproate crosses the placental barrier, hence should not be used in pregnancyÂ
Breastfeeding warnings:Â Â
The valproate is secreted in breastmilk Â
Pregnancy category:Â
Patient information leafletÂ
Generic Name:Â valproate sodium injection
Why do we use valproate sodium injection?Â
valproate sodium injection is used for various medical purposes. Here are some common reasons for its use:
Treatment of seizures: valproate sodium injection is primarily used in the management of seizures or epilepsy. It can be particularly effective in controlling absence seizures, generalized tonic-clonic seizures, and complex partial seizures.
Acute manic or mixed episodes associated with bipolar disorder: Valproate sodium injection may be used in the treatment of acute manic or mixed episodes associated with bipolar disorder. It can help stabilize mood and reduce symptoms such as irritability, impulsivity, and elevated mood.
Migraine prophylaxis: valproate sodium injection is sometimes utilized for the prevention of migraine headaches.
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