Microplastics and Misinformation: What Science Really Says
November 12, 2025
Brand Name :
Visudyne
Synonyms :
Verteporfin
Class :
Macular Degeneration Agents
Dosage Forms & StrengthsÂ
lyophilized power for reconstitutionÂ
15mg/vialÂ
Not determinedÂ
verteporfin: they may increase the serum concentration of Nonsteroidal Anti-Inflammatory Agents
verteporfin: they may increase the serum concentration of Nonsteroidal Anti-Inflammatory Agents
verteporfin: they may increase the serum concentration of Nonsteroidal Anti-Inflammatory Agents
verteporfin: they may increase the serum concentration of Nonsteroidal Anti-Inflammatory Agents
verteporfin: they may increase the serum concentration of Nonsteroidal Anti-Inflammatory Agents
methyl aminolevulinate topical
photosensitizing agents increase the effect of verteporfin
photosensitizing agents increase the effect of verteporfin
photosensitizing agents increase the effect of verteporfin
verteporfin: they may increase the antiplatelet effect of Agents with antiplatelet agentss
verteporfin: they may increase the antiplatelet effect of Agents with antiplatelet agentss
verteporfin: they may increase the antiplatelet effect of Agents with antiplatelet agentss
verteporfin: they may increase the antiplatelet effect of Agents with antiplatelet agentss
verteporfin: they may increase the antiplatelet effect of Agents with antiplatelet agentss
verteporfin: they may enhance the serum concentration of CYP2D6 Inhibitors
verteporfin: they may enhance the serum concentration of CYP2D6 Inhibitors
verteporfin: they may enhance the serum concentration of CYP2D6 Inhibitors
verteporfin: they may enhance the serum concentration of CYP2D6 Inhibitors
verteporfin: they may enhance the serum concentration of CYP2D6 Inhibitors
when both drugs are combined, there may be an increased risk of photosensitivity reactions 
photosensitizing agents increase the effect of photosensitization of verteporfin
Pirfenidone may increase the photosensitizing effect of verteporfin
may increase the photosensitizing effect
may increase the photosensitizing effect when combined
adapalene and benzoyl peroxideÂ
may increase the photosensitizing effect of photosensitizing agents
promethazine/dextromethorphanÂ
may increase the photosensitizing effect of Photosensitizing Agents
may increase the photosensitizing effect of Photosensitizing Agents
amiodarone: they may enhance the serum concentration of verteporfin
demeclocycline may reduce the therapeutic effect of the other drug by affecting intestinal flora
doxycycline may reduce the therapeutic effect of the other drug by affecting intestinal flora
photosensitizing agents increase the effect of verteporfin
Action and Spectrum:Â
Plasma transports verteporfin mainly with lipoproteins. When activated it produces reactive singlet oxygen and radicals, that cause damage to neovascular endothelium and vessel occlusion.Â
Frequency not definedÂ
Flashes of lightÂ
Severe vision lossÂ
PhotosensitivityÂ
Visual disturbancesÂ
EdemaÂ
HemorrhageÂ
InflammationÂ
HeadacheÂ
ConjunctivitisÂ
FeverÂ
Flu-like syndromeÂ
Atrial fibrillationÂ
Dry eyesÂ
Ocular itchingÂ
SubconjunctivalÂ
Back pain during infusionÂ
AstheniaÂ
Peripheral vascular disorderÂ
GI cancersÂ
NauseaÂ
Black box warning:Â
NoneÂ
Contraindications/caution:Â
Contraindications:Â
HypersensitivityÂ
PorphyriaÂ
Cautions:Â
In pregnancy and lactationÂ
Concurrent medicationsÂ
Cardiovascular eventsÂ
Pregnancy Warnings:Â
Pregnancy category: N/AÂ
Lactation: Excretion of the drug into the human breast milk is knownÂ
Pregnancy categories:Â
Pharmacology: Verteporfin generates reactive oxygen species under specific light, that causes harm to cells and vessels. It targets abnormal retinal blood vessels linked to specific eye diseases effectively.Â
Pharmacodynamics: Verteporfin injected intravenously to target abnormal blood vessels in neovascular AMD, and it reacts with light at 689 nm wavelength.Â
Pharmacokinetic:Â
Excretion and elimination:Â
It is excreted through feces and shows half-life of 30 hours.Â
Administration:Â
It is available in powder (lyophilized) form for intravenous use.Â
Patient information leaflet:Â
Generic Name: VerteporfinÂ
Why do we use Verteporfin?Â
Verteporfin is used in treatment of macular degeneration, pathologic myopia, and ocular histoplasmosis.Â
It is used in treatment of macular degeneration with choroidal neovascularization.Â